453-16-7

Usage

Uses

Used in Organic Synthesis:
3-Fluoro-1,2-propanediol is utilized as a solvent and intermediate, playing a crucial role in the synthesis of a wide range of organic compounds due to its unique chemical properties.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 3-fluoro-1,2-propanediol is employed as a reagent, contributing to the development and manufacturing of various medications.
Used in Agricultural Chemicals:
3-Fluoro-1,2-propanediol also serves as a reagent in the production of agricultural chemicals, aiding in the creation of substances that support crop protection and enhancement.
Used in Polymer Manufacturing:
With its potential applications in polymer science, 3-fluoro-1,2-propanediol is used in the manufacturing process of polymers, which have a broad spectrum of uses across different industries.
Used as a Building Block in Chemical Synthesis:
Furthermore, 3-fluoro-1,2-propanediol is recognized for its use as a building block in the synthesis of a variety of chemical compounds, highlighting its versatility in chemical research and development.
It is important to handle 3-fluoro-1,2-propanediol with care due to its moderately toxic nature, as it may cause irritation to the skin, eyes, and respiratory system upon exposure.

InChI:InChI=1/C3H7FO2/c4-3(1-5)2-6/h3,5-6H,1-2H2

Upstream product

• 503-09-3 epifluorohydrine 
• 96-24-2 3-monochloro-1,2-propanediol 
• 556-52-5 oxiranyl-methanol 
• 34331-41-4 4-fluoromethyl-2,2-dimethyl-[1,3]dioxolane 

Downstream Products

• 62522-66-1 4-Nitro-benzoic acid 3-fluoro-2-oxo-propyl ester 
• 32860-40-5 D-3-Deoxy-fluorglycerol-1-phosphat-dibenzylester 
• 142545-51-5 3-fluoro-1,2-propanediol 1-O-(4-methylbenzene)sulphonate 
• 32860-39-2 (2R)-3-fluoropropane-1,2-diol 
• 33644-25-6 (2S)-3-fluoropropane-1,2-diol 
• 53068-81-8 Hexadecanoic acid 1-fluoromethyl-2-hexadecanoyloxy-ethyl ester 
• 62522-65-0 1-Benzoyloxy-3-fluorpropan-2-on 
• 62522-72-9 3-fluoro-1,2-propanediol 1-O-benzoate 
• 60007-88-7 1-fluoro-3-(triphenylmethoxy)propan-2-ol 
• 57-03-4 lysophosphatidic acid 

Relevant academic research and scientific papers

The effects of substituting groups in cyclic carbonates for stable SEI formation on graphite anode of lithium batteries

Monofluoropropylene carbonate (MFPC) and trifluoropropylene carbonate (TFPC) with a monofluoromethyl (or trifluoromethyl) replacing the methyl group in propylene carbonate (PC) as well as EC-CH2CH2Si(CH3)2OSi(CH3)3 (Si-A) and EC-CH2CH2Si(CH3)3 (Si-B) have been synthesized. The charge-discharge studies in a Li/MCMB (mesocarbon microbeads) cell using electrolyte containing these compounds show that the solid electrolyte interphase (SEI) formation capability of MFPC/DMC (dimethyl carbonate) and TFPC/DMC are about the same as ethylene carbonate (EC)/DMC, and TFPC/PC/DMC is better than that of EC/PC/DMC, while MFPC/PC/DMC is poorer than the EC/PC/DMC. The superior SEI formation capability of TFPC could be attributed to the strong electron withdrawing group of CF3, which promote the "ring-opening" reaction. In contrast, the electron donating group CH3 in the PC structure may demote the "ring opening" and cause the poor SEI formation. The results of MFPC with weaker electron withdrawing group give further support of this hypothesis. The bi-solvent electrolytes of Si-A/DMC and Si-B/DMC have comparable SEI formation capability as EC/DMC and TFPC/DMC, regardless of their bulky chains. This indicates that if proper chain structures are used, good SEI formation capability could be obtained for cyclic carbonate with bulky chains. These new solvents provide valuable information in studying the SEI formation mechanism and designing new electrolytes.

Regioselective conversion of O-protected glycidols to fluorohydrins catalyuzed by tetrabutylammonium dihydrogentrifluoride under solid-liquid PTC conditions

A number of O-protected glycidols are regioselectively converted into the corresponding fluorohydrins FCH2CH(OH)CH2OX by reaction with catalytic amounts of Bu4N+H2F3- and a molar

TETRABUTYLAMMONIUM DIHYDROGENTRIFLUORIDE: AN EFFICIENT CATALYST FOR REGIO AND STEREOSELECTIVE CONVERSION OF EPOXIDES TO FLUOROHYDRINS UNDER SOLID-LIQUID PHASE-TRANSFER CATALYSIS CONDITIONS.

Tetrabutylammonium dihydrogentrifluoride is an efficient and easy-to-handle hydrofluorating agent in the ring-opening reaction of oxiranes to give good or excellent yields of fluorohydrins under solid-liquid PTC conditions.