4532-25-6

Basic information

• Product Name: 7-CHLOROIMIDAZO[1,2-A]PYRIDINE
• Synonyms: 7-Chloroimdazo[1,2-A]pyridine;7-CHLOROIMIDAZO[1,2-A]PYRIDINE 98%;7-Chloroimidazo[1,2-a]pyridine;7-Chloroimidazo[1,2-a]pyr...;IMidazo[1,2-a]pyridine, 7-chloro-
• CAS NO: 4532-25-6
• Molecular Formula: C₇H₅ClN₂
• Molecular Weight: 152.58
• Product Categories: Heterocycle-Pyridine series
• Mol File: 4532-25-6.mol
• Article Data: 14

Chemical Properties

• Melting Point: 49-51 ºC
• Appearance: /
• Density: 1.35
• Refractive Index: 1.653
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 5.21±0.50(Predicted)
• CAS DataBase Reference: 7-CHLOROIMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-CHLOROIMIDAZO[1,2-A]PYRIDINE(4532-25-6)
• EPA Substance Registry System: 7-CHLOROIMIDAZO[1,2-A]PYRIDINE(4532-25-6)

Safety Data

• Hazardous Substances Data: 4532-25-6(Hazardous Substances Data)

Usage

General Description

7-Chloroimidazo[1,2-a]pyridine is a chemical compound with the molecular formula C7H5ClN2. It is a heterocyclic compound with a fused imidazole and pyridine ring system, and the chlorine atom is located at the 7-position of the molecule. 7-CHLOROIMIDAZO[1,2-A]PYRIDINE is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential biological activities, including its role as an inhibitor of kinase enzymes and its anti-inflammatory properties. 7-Chloroimidazo[1,2-a]pyridine may also have applications in the development of new materials and chemical processes due to its unique structure and reactivity.

InChI:InChI=1/C7H5ClN2/c8-6-1-3-10-4-2-9-7(10)5-6/h1-5H

Upstream product

• 5470-22-4 4-chloropicolinic acid 
• 19798-80-2 2-Amino-4-chloropyridine 
• 17157-48-1 bromoacetaldehyde 
• 130721-78-7 tert-butyl (4-chloropyridin-2-yl) carbamate 
• 107-20-0 2-chloroethanal 

Downstream Products

• 1421589-68-5 7-chloro-3-(4-ethoxyphenyl)imidazo[1,2-a]pyridine 
• 1421589-41-4 3-(4-ethoxyphenyl)-N-[(4-ethylphenyl)-methyl]imidazo[1,2-a]pyridin-7-amine 

Relevant articles and documents

Synthesis method of imidazopyridine or pyrimidine derivative

The invention belongs to the technical field of synthesis, and particularly relates to a synthesis method of an imidazopyridine or pyrimidine derivative. The imidazopyridine or pyrimidine compound is obtained by taking pyridine or pyrimidinecarboxylic acid as a synthon through amidation, Hofmann degradation and cyclization reaction, and the obtained imidazopyridine or pyrimidine derivative can be further converted to generate a functional product. The method has the advantages of easily available raw materials, simple operation, high reaction efficiency, convenient post-treatment, and diversity of functional groups.

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