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Benzenesulfonothioic acid, 4-iodo, S-(4-iodophenyl) ester, also known as 4-iodobenzenesulfonothioic acid S-(4-iodophenyl) ester, is a chemical compound with the molecular formula C12H8I2O2S2. This organic compound features a benzene ring with a sulfonothioic acid group attached to it, which is further esterified with a 4-iodophenyl group. The presence of two iodine atoms in the molecule enhances its reactivity and stability, making it a potentially useful intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. The compound's unique structure and properties may also contribute to its applications in research and development, particularly in the fields of organic synthesis and materials science.

4533-14-6

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4533-14-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4533-14-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,3 and 3 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4533-14:
(6*4)+(5*5)+(4*3)+(3*3)+(2*1)+(1*4)=76
76 % 10 = 6
So 4533-14-6 is a valid CAS Registry Number.

4533-14-6Downstream Products

4533-14-6Relevant academic research and scientific papers

Temperature-controlled selective reduction of arenesulfonyl chlorides promoted by samarium metal in DMF

Liu, Yongjun,Zhang, Yongmin

, p. 4291 - 4294 (2003)

Promoted by samarium in DMF, arenesulfonyl chlorides can be selectively reduced to diaryldisulfones, diarylthiosulfonates and diaryldisulfides in good to excellent yields by reaction temperature control without the need to pretreat or activate the metallic samarium.

Synthesis of Symmetrical Thiosulfonates via Cu(OTf)2-Catalyzed Reductive Homocoupling of Arenesulfonyl Chlorides

Liu, Lixia,Luo, Bo,Wang, Chengming

supporting information, p. 5880 - 5883 (2021/11/27)

A variety of symmetrical thiosulfonates are synthesized via Cu-catalyzed reductive homocoupling of aryl sulfonyl chlorides. This protocol uses organic amine acting as a mild reductant and low-cost copper as an effective catalyst. Such a reductive coupling process features a broad substrate scope and good functional group tolerance. Related thiosulfonate products can also be converted into diverse functional molecules.

Tunable and Practical Synthesis of Thiosulfonates and Disulfides from Sulfonyl Chlorides in the Presence of Tetrabutylammonium Iodide

Zheng, Yong,Qing, Feng-Ling,Huang, Yangen,Xu, Xiu-Hua

supporting information, p. 3477 - 3481 (2016/11/13)

A tunable and practical synthesis of electrophilic sulfenylating reagents, thiosulfonates and disulfides, from inexpensive and easily available sulfonyl chlorides, has been developed. By appropriate choice of solvents, the reaction of sulfonyl chlorides and tetrabutylammonium iodide gave the target products in good to excellent yields, respectively. These transformations probably proceed through a reducing–coupling pathway. (Figure presented.).

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