4538-39-0Relevant articles and documents
Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists
Kagermeier, Nicole,Werner, Kristin,Keller, Max,Baumeister, Paul,Bernhardt, Günther,Seifert, Roland,Buschauer, Armin
, p. 3957 - 3969 (2015/02/19)
The bioisosteric replacement of the acylguanidine moieties in dimeric histamine H2 receptor (H2R) agonists by carbamoylguanidine groups resulted in compounds with retained potencies and intrinsic activities, but considerably improved
A family of hydrogels based on ureido-linked aminopolyol-derived amphiphiles and bolaamphiphiles: Synthesis, gelation under thermal and sonochemical stimuli, and mesomorphic characterization
Avalos, Martin,Babiano, Reyes,Cintas, Pedro,Gomez-Carretero, Antonio,Jimenez, Jose L.,Lozano, Marina,Ortiz, Angel L.,Palacios, Juan C.,Pinazo, Aurora
experimental part, p. 5656 - 5669 (2009/06/05)
This article describes the systematic preparation of a novel family of carbohydrate amphiphiles and bolaamphiphiles in which hydrophilic and hydrophobic units are connected via a ureido or bis(ureido) moiety. The sugar core is derived from aminopolyols such as D-glucamine (1), N-methyl-D-glucamine (2), or the sugar-like species tris(hydroxymethyl)aminomethane (3). The O-unprotected derivatives behave as self-organizing nonionic surfactants with good water gelation ability, which can be induced under thermal or ultra-sound-driven stimuli. In addition, some derivatives of 1 and 2, and rarely 3 also formed lyotropic liquid crystals with lamellar or hexagonal structures that exhibit low-temperature transitions.