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454-15-9

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454-15-9 Usage

General Description

2-BROMOMETHYL-1-FLUORO-4-NITROBENZENE is a compound with the molecular formula C7H5BrFNO2. It is a derivative of benzene with a bromine atom, a fluorine atom, and a nitro group attached to different carbon atoms. This chemical is mainly used as an intermediate for the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used in the manufacturing of dyes and pigments, as well as in organic synthesis processes. Additionally, it is known to exhibit moderate toxicity and should be handled and stored with appropriate precautions.

Check Digit Verification of cas no

The CAS Registry Mumber 454-15-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,5 and 4 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 454-15:
(5*4)+(4*5)+(3*4)+(2*1)+(1*5)=59
59 % 10 = 9
So 454-15-9 is a valid CAS Registry Number.

454-15-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(Bromomethyl)-1-fluoro-4-nitrobenzene

1.2 Other means of identification

Product number -
Other names 4-fluoro-3-bromomethylnitrobenzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:454-15-9 SDS

454-15-9Relevant articles and documents

(PYRIDIN-2-YL)AMINE DERIVATIVES AS TGF-BETA R1 (ALK5) INHIBITORS FOR THE TREATMENT OF CANCER

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Paragraph 00305-00306, (2020/07/15)

The present invention relates to pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment and/or prevention of a proliferation disorder associated with ΤGFβR1 activity, such as a cancer or fibrosis. The invention provides compounds of Formula (I) and Formula (II) as further described herein having an acidic moiety that enhances tissue specificity for targeted tissues and organs. The invention includes pharmaceutical compositions, pharmaceutical combinations, and methods of use of these compounds for treating conditions including cancer or fibrosis.

THERAPEUTIC COMPOUNDS

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Paragraph 0395; 0403; 0404, (2017/01/23)

The invention provides compounds of formula (I): wherein, A, C, D, X, and Y have any of the values defined in the specification, and salts thereof. The compounds are SIRT2 inhibitors and are useful for treating SIRT2 associated conditions.

Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases

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Page/Page column 69, (2013/06/27)

The invention relates to dihydronaphthyridines and related compounds; compositions comprising an effective amount of a dihydronaphthyridine or a related compound; and methods for treating or preventing proliferative diseases comprising the administration of an effective amount of a dihydronaphthyridine or a related compound.

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