454-67-1

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
3-Amino-5-fluorobenzotrifluoride is utilized as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique chemical structure and properties make it a valuable component in the development of new drugs and agricultural chemicals.
Used in Enzyme Inhibition:
3-Amino-5-fluorobenzotrifluoride serves as a potent inhibitor of the enzyme fatty acid amide hydrolase (FAAH). This enzyme is involved in the regulation of endocannabinoid signaling, which is associated with various physiological processes, including pain, appetite, and mood regulation. By inhibiting FAAH, 3-Amino-5-fluorobenzotrifluoride can potentially modulate these processes and contribute to the development of therapeutic agents for related conditions.
Used in Electronics and Polymer Materials Production:
3-Amino-5-fluorobenzotrifluoride is also employed in the production of electronics and polymer materials. Its specific chemical properties may contribute to the development of advanced materials with improved performance characteristics for use in various electronic devices and applications.
Safety Precautions:
Due to its toxic and potentially harmful nature, 3-Amino-5-fluorobenzotrifluoride must be handled with care. Proper safety measures, including the use of personal protective equipment and adherence to safety protocols, should be taken to minimize the risk of exposure and ensure the safe handling of this chemical compound.

InChI:InChI=1/C7H3F4NO2/c8-5-1-4(7(9,10)11)2-6(3-5)12(13)14/h1-3H

Upstream product

• 917391-24-3 2-bromo-5-fluoro-1-nitro-3-trifluoromethyl-benzene 
• 401-99-0 3,5-dinitrobenzotrifluoride 
• 454-73-9 1-fluoro-3-(trifluoromethyl)-5-nitrobenzene 

Downstream Products

• 210992-82-8 1-[3-Fluoro-5-(trifluoromethyl)phenyl]-piperazine 
• 302912-19-2 3-fluoro-5-(trifluoromethyl)phenyl isocyanate 
• 641571-11-1 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline 
• 642049-72-7 C₃₃H₃₂F₄N₄O 
• 630116-32-4 2-chloro-N-(3-fluoro-5-trifluoromethylphenyl)-acetamide 
• 503183-20-8 4-[(3-fluoro-5-trifluoromethylphenyl)hydrazono]-4H-pyrazole-3,5-diamine 
• 618461-71-5 4-[1-(4-tert-Butylphenyl)-3-(3-fluoro-5-trifluoromethylphenyl)ureidomethyl]-N-(5-oxo-4,5-dihydro[1,2,4]oxadiazol-3-ylmethyl)benzamide 
• 1027973-04-1 3-[4-(3-fluoro-5-trifluoromethyl-phenyl)-piperazin-1-yl]-1-(5-methyl-1-pyrimidin-2-yl-1H-pyrazol-4-yl)-propan-1-one 

Relevant academic research and scientific papers

PROCESS FOR THE SYNTHESIS OF ORGANIC COMPOUNDS

The present invention provides an efficient, safe and cost effective way to prepare 5 (4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzenamine which is a key intermediate for the preparation of substituted pyrimidinylaminobenzamides of formula (II).