4541-13-3Relevant academic research and scientific papers
Branch hydroxyoxaalkylmelamine chain and its use has compd.
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Paragraph 0116, (2018/07/28)
PROBLEM TO BE SOLVED: To provide a means capable of lowering the melting point or the glass transition point of a compound having straight chain alkyl chain or a compound having straight chain oxaalkyl chain and also lowering the viscosity including the kinematic viscosity or the like, and to provide a compound obtained by the means and a use of the compound. SOLUTION: The compound has an oxaalkyl chain which has at least one side chain, in a molecule. COPYRIGHT: (C)2012,JPOandINPIT
Synthesis and antiproliferative activity of alkylphosphocholines
Agresta, Mandy,D'Arrigo, Paola,Fasoli, Ezio,Losi, Daniele,Pedrocchi-Fantoni, Giuseppe,Riva, Simona,Servi, Stefano,Tessaro, Davide
, p. 201 - 210 (2007/10/03)
Alkylphosphocholines (APC) with one or more methylene groups in the alkyl chain replaced by oxygen atoms or carbonyl groups, or both have been assembled modularly using ω-diols as central building blocks. Out of 25 new compounds of this kind, 11 were evaluated for their antiproliferative activity on four cell lines and compared with miltefosine to evaluate their hemolytic activity (HA) and cytotoxicity on non-tumoral cells (MT2), used as markers of adverse effects. Compound 13 was more active on cancer cell lines than on non-tumoral cells and the data were similar for MTT and thymidine incorporation assays. It had less HA than miltefosine. Compound 13 could therefore be a candidate for the preparation of compounds with higher cytotoxicity on cancer cells and lower general toxicity.
Omega-hydrofluoroalkyl ethers, precursor carboxylic acids and derivatives thereof, and their preparation and application
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Page 17, (2010/01/31)
Normally liquid, omega-hydrofluoroalkyl ether compounds (and selected mixtures thereof) have a saturated perfluoroaliphatic chain of carbon atoms interrupted by one or more ether oxygen atoms. The compounds can be prepare, e.g. by decarboxylation of the corresponding fluoroalkyl ether carboxylic acids and are useful, e.g., in cleaning and drying applications.
