454180-54-2

Upstream product

• 321526-62-9 (2S,5'S)-5'-(2,2-Dimethoxy-ethyl)-4-((R)-2-hydroxy-1-methyl-ethyl)-2,5'-diisobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-[2,3']bipyrrolyl-1,1'-dicarboxylic acid dibenzyl ester 
• 321526-61-8 (2S,5'S)-5'-(2,2-Dimethoxy-ethyl)-2,5'-diisobutyl-4-[(R)-1-methyl-2-(2-trimethylsilanyl-ethoxymethoxy)-ethyl]-3,4'-dioxo-2,3,4',5'-tetrahydro-[2,3']bipyrrolyl-1,1'-dicarboxylic acid dibenzyl ester 
• 321526-57-2 (S)-4-benzyl-3-((R)-2,5-dimethylhex-4-enoyl)oxazolidin-2-one 
• 454180-52-0 [2-((R)-2,5-Dimethyl-hex-4-enyloxymethoxy)-ethyl]-trimethyl-silane 
• 321526-58-3 (R)-3-Methyl-4-(2-trimethylsilanyl-ethoxymethoxy)-butyraldehyde 
• 154388-63-3 (R)-2,5-dimethylhex-4-en-1-ol 
• 321526-60-7 (2S,5'S)-5'-(2,2-Dimethoxy-ethyl)-2,5'-diisobutyl-4-[(R)-1-methyl-2-(2-trimethylsilanyl-ethoxymethoxy)-ethyl]-1,2,1',5'-tetrahydro-[2,3']bipyrrolyl-3,4'-dione 
• 321526-59-4 (S)-2-(2,2-Dimethoxy-ethyl)-2-isobutyl-4-[(R)-1-methyl-2-(2-trimethylsilanyl-ethoxymethoxy)-ethyl]-1,2-dihydro-pyrrol-3-one 
• 454180-53-1 {(S)-2-Isobutyl-4-[(R)-1-methyl-2-(2-trimethylsilanyl-ethoxymethoxy)-ethyl]-3-oxo-2,3-dihydro-1H-pyrrol-2-yl}-acetaldehyde 

Downstream Products

• 321526-63-0 (2S,5'S)-5'-(2,2-Dimethoxy-ethyl)-4-((R)-1-ethoxycarbonyl-ethyl)-2,5'-diisobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-[2,3']bipyrrolyl-1,1'-dicarboxylic acid dibenzyl ester 
• 321526-64-1 (2S,5'S)-5'-Carboxymethyl-4-((R)-1-ethoxycarbonyl-ethyl)-2,5'-diisobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-[2,3']bipyrrolyl-1,1'-dicarboxylic acid dibenzyl ester 
• 454180-55-3 (2S,5'S)-5'-(Benzyloxycarbamoyl-methyl)-4-((R)-1-ethoxycarbonyl-ethyl)-2,5'-diisobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-[2,3']bipyrrolyl-1,1'-dicarboxylic acid dibenzyl ester 

Relevant academic research and scientific papers

Design, Synthesis, and Evaluation of a Pyrrolinone-based Matrix Metalloprotease Inhibitor

formula presented A pyrrolinone-based hydroxamate matrix metalloprotease inhibitor, (-)-1, has been designed and synthesized. Enzymatic assay revealed that (-)-1 inhibited three of the ten matrix metalloprotease enzymes examined and as such represents a n