454218-37-2 Usage
Chemical structure
1-Piperidinesulfonamide, N-[4-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]is a complex organic compound containing a piperidine ring, sulfonamide group, and various aromatic and hydroxyethyl moieties.
Pharmaceutical intermediate
1-Piperidinesulfonamide,
N-[4-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]- is commonly used as a pharmaceutical intermediate in the synthesis of potential drug candidates and bioactive compounds.
Bioactive properties
The compound may have bioactive properties due to its presence in the structure and may potentially interact with biological systems through binding to specific targets or receptors.
Further research needed
More research and studies are needed to fully understand the pharmacological and physiological effects of this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 454218-37-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,4,2,1 and 8 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 454218-37:
(8*4)+(7*5)+(6*4)+(5*2)+(4*1)+(3*8)+(2*3)+(1*7)=142
142 % 10 = 2
So 454218-37-2 is a valid CAS Registry Number.
454218-37-2Relevant academic research and scientific papers
Potent and selective, sulfamide-based human β3-adrenergic receptor agonists
Dow, Robert L.,Paight, Ernest S.,Schneider, Steven R.,Hadcock, John R.,Hargrove, Diane M.,Martin, Kelly A.,Maurer, Tristan S.,Nardone, Nancy A.,Tess, David A.,DaSilva-Jardine, Paul
, p. 3235 - 3240 (2007/10/03)
A series of sulfamide-based analogs related to L-796568 were prepared and evaluated for their biological activity at the human β3- adrenergic receptor (AR). This modification allows for a significant reduction in molecular weight, while maintai
Beta3 agonists and uses thereof
-
, (2008/06/13)
Sulfamide compounds having formula (I) are described as well as their use in the treatment of diseases dependent on the signaling pathways associated with β-adrenergic receptors, such as obesity, diabetes, hypertension, gastrointestinal hypo- or hyper-mot
Sulfamide derivatives useful as beta3 agonists and pharmaceutical uses thereof
-
Page 23, (2010/01/31)
Sulfamide compounds having formula (I) are described as well as their use in the treatment of diseases dependent on the signaling pathways associated with β-adrenergic receptors, such as obesity, diabetes, hypertension, gastrointestinal hypo- or hyper-motility and cardiovascular diseases.
