454452-97-2

Upstream product

• 32004-66-3 5-fluoro-2-methyl-1H-indene-3-acetic acid 
• 20989-17-7 (2S)-2-phenylglycinol 
• 25952-53-8 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride 

Downstream Products

• 1055073-24-9 (Z)-5-Fluoro-2-Methyl-(4-Pyridinylidene)-3-(N-(S-α-Hydroxymethyl)Benzyl)-Indenylacetamide 

Relevant academic research and scientific papers

Method for treating a patient with neoplasia using Iressa

This invention provides a method for treating a patient with neoplasia by an adjuvant therapy that includes treatment with an inhibitor of human epidermal growth factor receptor tyrosine kinase and a cGMP-specific phosphodiesterase inhibitor.

Substituted condensation products of n-benzyl-3-indenyl acetamides with heterocyclic aldehydes

Substituted condensation products of N-benzyl-3-indenylacetamides with heterocyclic aldehydes are useful for inducing or promoting apotosis and for arresting uncontrolled neoplastic cell proliferation, and are specifically useful in the arresting and treatment of neoplasias, including precancerous and cancerous lesions.