4545-85-1

Upstream product

• 780-24-5 dibenzylmercury(II) 
• 100-44-7 benzyl chloride 
• 14990-01-3 benzylphosphine 
• 76684-22-5 C₇H₆ClP 
• 74483-17-3 chlorophosphane 
• 76684-21-4 Phenylmethylidynephosphine 
• 1080-32-6 O,O-diethyl benzylphosphonate 
• 100-39-0 benzyl bromide 
• 1589-82-8 phenylmagnesium bromide 

Downstream Products

• 36103-43-2 diethyl benzylphosphonite 
• 24681-03-6 Benzylphosphinsaeure-diisobutylester 
• 56522-07-7 Benzyl-tert-butylphosphinous Chloride 
• 56522-05-5 Isopropylbenzylchlorphosphin 
• 1499-19-0 benzylphosphonic dichloride 
• 129216-63-3 Benzylbis(phenylethynyl)phosphan 
• 97972-04-8 benzyldiethinylphosphane 
• 6881-57-8 benzylphosphonic acid 
• 444312-98-5 2,2'-(benzylphosphiniden)bisfuran 
• 76684-22-5 C₇H₆ClP 
• 141868-67-9 Benzyl-bis-(3-fluoro-phenyl)-phosphane 
• 120011-48-5 Benzyl-bis-(4-trimethylsilanyl-phenyl)-phosphane 
• 85363-47-9 (2Z,4Z,6Z)-9-Benzyl-9-phospha-bicyclo[6.1.0]nona-2,4,6-triene 
• 141868-68-0 Benzyl-bis-(4-fluoro-phenyl)-phosphane 

Relevant academic research and scientific papers

Hydrogen/Halogen Exchange of Phosphines for the Rapid Formation of Cyclopolyphosphines

The hydrogen/halogen exchange of phosphines has been exploited to establish a truly useable substrate scope and straightforward methodology for the formation of cyclopolyphosphines. Starting from a single dichlorophosphine, a sacrificial proton "donor phosphine"makes the rapid, mild synthesis of cyclopolyphosphines possible: reactions are complete within 10 min at room temperature. Novel (aryl)cyclopentaphosphines (ArP)5 have been formed in good conversion, with the crystal structures presented. The use of catalytic quantities of iron(III) acetylacetonate provides significant improvements in conversion in the context of diphosphine (Ar2P)2 and alkyl-substituted cyclotetra- or cyclopentaphosphine ((AlkylP)n, where n = 4 or 5) formation. Both iron-free and iron-mediated reactions show high levels of selectivity for one specific ring size. Finally, investigations into the reactivity of Fe(acac)3 suggest that the iron species is acting as a sink for the hydrochloric acid byproduct of the reaction.

A new method for the synthesis of dichlorophosphines

A new method for the synthesis of alkyldichlorophosphines by chlorination of alkylphosphines with phosphorus pentachloride under mild conditions is described.

5,16-Dialkyl(diaryl)-5,16-dihydro-5,16-diphospha-tetraepoxy[22]annulene (2.1.2.1)

Several 5,16-dialkyl(diaryl)-5,16-dihydro-5,16-diphospha-tetraepoxy[22]annulenes (2.1.2.1) 9 as possible precursors of aromatic 5,16-diphospha-tetraepoxy[22]annulenes(2.1.2.1) 8 are synthesized by cyclizing Wittig-reactions of the phosphane dialdehydes 15 with the bis-ylids of the phosphane-bisphosphoniumsalts 19.

Synthesis and properties of nonpolar DNA (arylalkyl)phosphonates

The eight (arylalkyl)-modified phosphoramidites (=(arylalkyl)phosphonamidites) 1-8 (Fig. 2) were synthesized (Schemes 1-3) and incorporated at different positions into 2′-deoxyoligonucleotides. The [P(R)]-and [P(S)]-diastereoisomers of the hexanucleotides

Phenylalkyl backbone modified oligodeoxynucleotides, their synthesis and the influence of the alkyl chain length

Phenylalkyl modified phosphoramidites (alkyl chain length n = 1, 2, 3, 5; Fig. 1) were synthesised and incorporated into a DNA hexamer (5′-d(GCCp-GCG); p = place of modification). The obtained diastereomeres were separated by RP-HPLC. After hybridisation

Synthesis and Structure of 1,4-Dihydro-1,4-diphosphinines and 1,4-Dihydro-1,4-phospharsinines

The cyclizing addition of phenylphosphane or phenylarsane to tert-butyl(benzyl, diethylamino)diethinylphosphane (14) with formation of the 1,4-dihydro-1,4-diphosphinines 11a - d and 1,4-dihydro-1,4-phospharsinines 12a - d, resp., occurs by a radical mecha