4547-58-4

Usage

InChI:InChI=1/C14H20O3/c1-3-5-10-17-13-8-6-12(7-9-13)11-14(15)16-4-2/h6-9H,3-5,10-11H2,1-2H3

Upstream product

• 64-17-5 ethanol 
• 201230-82-2 carbon monoxide 
• 10519-06-9 1-butoxy-4-methylbenzene 
• 5736-88-9 p-butoxybenzaldehyde 
• 66786-80-9 1-Butoxy-4-((Z)-2-methanesulfinyl-2-methylsulfanyl-vinyl)-benzene 

Downstream Products

• 4547-57-3 4-butoxyphenylacetic acid 
• 220531-49-7 C₁₄H₁₉BrO₃ 
• 15560-23-3 N-Hydroxy-4-butoxy-α-methyl-phenylacetamide 
• 15560-38-0 2-(4-Butoxy-phenyl)-2-methyl-propionic acid ethyl ester 
• 15560-35-7 2-(4-Butoxy-phenyl)-propionic acid ethyl ester 

Relevant academic research and scientific papers

PROCESS FOR SYNTHESIZING PHENYLACETIC ACID BY CARBONYLATION OF TOLUENE

A production process for substituted phenylacetic acids or ester analogues thereof is disclosed. In this process toluene or toluene substituted with various substituents, an alcohol, an oxidant and carbon monoxide are used as raw materials to obtain compounds comprising structure of phenylacetic acid ester or analogues thereof by catalysis of the complex catalyst formed from transition metal and ligand, and such compounds are hydrolyzed to obtain various substituted phenylacetic acid based compounds. This type of compounds and their derivatives serve as important fine chemicals used widely in the industries of pharmaceuticals, pesticides, perfume and the like.

Palladium-catalyzed oxidative carbonylation of benzylic C-H bonds via nondirected C(sp3)-H activation

A new strategy for generating benzylpalladium reactive species from toluenes via nondirected C(sp3)-H activation has been developed. This led to construction of an efficient Pd-catalyzed reaction protocol for the oxidative carboxylation of benzylic C-H bonds to form substituted 2-phenylacetic acid esters and derivatives from inexpensive, commercially available starting materials.

Growth hormone secretagogues

What is disclosed are growth hormone secretagogues, and their uses, of the formula wherein R1 is C6H5CH2OCH2—, C6H5(CH2)3— or indol-3-ylmethyl; Y is pyrrolidin-1-yl, 4-C1-C6alkylpiperidin-1-yl or NR2R2; R2 are each independently a C1to C6alkyl; R3 is 2-napthyl or phenyl para-substituted by W; W is H, F, CF3, C1-C6alkoxy or phenyl; and R4 is H or CH3, or a pharmaceutically acceptable salt or solvate thereof.