454709-69-4Relevant academic research and scientific papers
XANTHINE DERIVATIVES, PRODUCTION THEREOF AND USE THEREOF AS MEDICINES
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Page/Page column 31, (2008/06/13)
The invention concerns substituted xanthines of general formula (I), wherein: R1 to R4 are such as defined in Claim 1, and tautomers, stereoisomers, mixtures, prodrugs and salts thereof. Said compounds have advantageous pharmacological properties, in particular an inhibiting effect on the activity of the dipeptidyl peptidase IV (DPP-IV) enzyme.
Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
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, (2008/06/13)
The present invention relates to substituted xanthines of general formula wherein R1 to R4 are defined as in claim 1, the tautomers and the stereoisomers thereof, mixtures thereof, the prodrugs and the salts thereof which have valuable pharmacological properties, particularly an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).
