455-25-4

Upstream product

• 13329-40-3 4-Iodoacetophenone 
• 350-47-0 1-(4-acetylphenyl)diazonium tetrafluoroborate 
• 1788-10-9 4-Acetylbenzenesulfonyl chloride 

Downstream Products

• 140682-26-4 4-[(E)-3-(4-Nitro-phenyl)-acryloyl]-benzenesulfonyl fluoride 
• 92-91-1 biphenyl-4-acetaldehyde 
• 456-11-1 4-(N-dichloroacetyl-glycyl)-benzenesulfonyl fluoride 
• 100958-92-7 4-bromoacetyl-benzenesulfonyl azide 
• 322-31-6 4-dibromoacetyl-benzenesulfonyl fluoride 
• 345-84-6 4-(N-dichloroacetyl-seryl)-benzenesulfonyl fluoride 
• 322-14-5 4-[(1RS,2RS)-2-(2.2-dichloro-acetylamino)-1.3-dihydroxy-propyl]-benzenesulfonyl fluoride 
• 140682-35-5 4-[2,3-Dibromo-3-(4-nitro-phenyl)-propionyl]-benzenesulfonyl fluoride 
• 140682-38-8 4-(2,3-Dibromo-3-phenyl-propionyl)-benzenesulfonyl fluoride 
• 75177-14-9 4-acetylbenzenesulfonyl azide 

Relevant academic research and scientific papers

Efficient synthesis of chalcone-4′-sulfonyl chlorides and fluorides

A library of 4′-chloro- and 4′-fluorosulfonyl-substituted chalcones was prepared via the aldol-type condensation reactions of 4-acetylbenzene-1-sulfonyl halides with various aromatic aldehydes, either in absolute ethanol or glacial acetic acid, in the pre

Visible-Light-Mediated Synthesis of Sulfonyl Fluorides from Arylazo Sulfones

Sulfonyl fluorides are useful motifs for a wide range of applications in organic synthesis including sulfur (VI) fluoride exchange-based “click chemistry.” Herein, a visible-light-mediated synthesis of sulfonyl fluorides from arylazo sulfones is described. In the present study, K2S2O5 and N-fluorobenzenesulfonimide (NFSI) were used as the sulfonyl source and fluorinating agent, respectively, for visible-light-mediated fluorosulfonylation of arylazo sulfones to prepare various sulfonyl fluorides in 60–85% yield. This protocol is a synthetic approach to provide useful sulfonyl fluoride structures at room temperature. (Figure presented.).

Pd-Catalyzed Conversion of Aryl Iodides to Sulfonyl Fluorides Using SO2 Surrogate DABSO and Selectfluor

A one-pot Pd-catalyzed conversion of aryl iodide to aryl sulfonyl fluorides using DABSO and Selectfluor has been developed generating aryl sulfonyl fluorides in good to excellent yields. The reaction results in the generation of electronically and sterically diverse sulfonyl fluorides. Additionally, sulfonyl fluorides can be converted to aryl sulfonamides and sulfonic esters using Cs2CO3 under mild conditions.