455264-53-6

Basic information

• Product Name: 7-Oxaspiro[3.5]nonane-1,3-dione
• Synonyms: 7-Oxaspiro[3.5]nonane-1,3-dione
• CAS NO: 455264-53-6
• Molecular Formula: C₈H₁₀O₃
• Molecular Weight: 154.1632
• Mol File: 455264-53-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-Oxaspiro[3.5]nonane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Oxaspiro[3.5]nonane-1,3-dione(455264-53-6)
• EPA Substance Registry System: 7-Oxaspiro[3.5]nonane-1,3-dione(455264-53-6)

Safety Data

• Hazardous Substances Data: 455264-53-6(Hazardous Substances Data)

Upstream product

• 40191-32-0 tetrahydro-2H-pyran-4-carbonylchloride 
• 5337-03-1 tetrahydro-2H-pyran-4-carboxylic acid 
• 455264-52-5 3-ethoxy-7-oxaspiro[3.5]non-2-en-1-one 

Downstream Products

• 455262-48-3 ethyl (2S)-2-[(3-oxo-7-oxaspiro[3.5]non-1-en-1-yl)amino]-3-{4-[(3,5-dichloroisonicotinoyl)amino]phenyl}propanoate 
• 1072115-55-9 (S)-2-(2-bromo-3-oxo-7-oxa-spiro[3.5]non-1-en-1-ylamino)-3-[2-(2,6-dichloro-phenyl)-quinolin-6-yl]-propionic acid 
• 1072115-59-3 methyl (2S)-3-(2-(2,6-dichlorophenyl)quinolin-6-yl)-2-((2-bromo-3-oxo-7-oxa-spiro(3.5)non-1-en-1-yl)amino)propanoate 
• 1072115-58-2 methyl (2S)-3-(2-(2,6-dichlorophenyl)quinolin-6-yl)-2-((3-oxo-7-oxa-spiro(3.5)non-1-en-1-yl)amino)propanoate 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF PHENYLALANINE ENAMIDE DERIVATIVES

A process for the preparation of a class of phenylalanine enamide derivatives is described formula (1) wherein: Ar1 is an optionally substituted aromatic or heteroaromatic group; L2 is a linker group selected from -N(R4)- [where R4 is a hydrogen atom or an optionally substituted straight or branched C1-6alkyl group], -CON(R4)-, or -S(O)2N(R4)-; R1 is a carboxylic acid (-CO2H) or a derivative or biostere thereof; R2 is a hydrogen atom or a C1-6alkyl group; Rx, Ry and Rz which may be the same or different is each an atom or group -L1(Alk1)n(R3)v; and the salts, solvates, hydrates and N-oxides thereof; which comprises reacting a compound of formula (2): wherein: Qa is a group -N(R4)H; and the salts, solvates, hydrates and N-oxides thereof; with a compound Ar1W wherein W is a group selected from X1 (wherein X1 is a leaving atom or group), -COX2 (wherein X2 is a halogen atom or a -OH group) or -SO2 X3 (in which X3 is a halogen atom).