455312-11-5

Upstream product

• 1461-22-9 tributyltin chloride 
• 211619-36-2 N-methyl-N-(2-nitrobenzyl)carbamoyl chloride 
• 455312-10-4 (R)-5-(3-Trimethylsilanyl-prop-2-ynyl)-oxazolidin-2-one 

Downstream Products

• 455312-08-0 (3aS,4S,5S,6aR)-4-[(2-Nitro-benzyl)-(1H-pyrrole-2-carbonyl)-amino]-2-oxo-5-(toluene-4-sulfonyl)-tetrahydro-cyclopentaoxazole-3-carboxylic acid methyl-(2-nitro-benzyl)-amide 
• 474671-05-1 (3aS,4S,5S,6aR)-4-(2-Nitro-benzylamino)-2-oxo-5-(toluene-4-sulfonyl)-tetrahydro-cyclopentaoxazole-3-carboxylic acid methyl-(2-nitro-benzyl)-amide 
• 455312-14-8 1-methyl-1-(2-nitro-benzyl)-3-[4-(2-nitro-benzyl)-2,5-dioxo-2,3,3a,4,5,8b-hexahydro-1H-4,8a-diaza-as-indacen-3-yl]-urea 
• 455312-09-1 (3aS,6aR)-2-Oxo-5-(toluene-4-sulfonyl)-6,6a-dihydro-3aH-cyclopentaoxazole-3-carboxylic acid methyl-(2-nitro-benzyl)-amide 

Relevant academic research and scientific papers

Alkynyliodonium salts in organic synthesis. Application to the total synthesis of (-)-Agelastatin A and (-)-Agelastatin B

The asymmetric total syntheses of (-)-agelastatin A and (-)-agelastatin B were accomplished in 14 steps each from (R)-epichlorohydrin. The pivotal transformation in both sequences was a sulfinate-promoted cyclization of an alkynyliodonium salt to furnish