45588-79-2

Basic information

• Product Name: 4-(AMINOMETHYL)-PYRIMIDINE
• Synonyms: 4-(AMINOMETHYL)-PYRIMIDINE;4-PYRIMIDINE METHANAMINE;4-Pyrimidinemethanamine (9CI);pyrimidin-4-ylmethanamine;(pyrimidin-4-ylmethyl)amine(SALTDATA: 2HCl);(pyrimidin-4-ylmethyl)amine dihydrochloride;C-Pyrimidin-4-yl-methylamine
• CAS NO: 45588-79-2
• Molecular Formula: C₅H₇N₃
• Molecular Weight: 109.13
• Product Categories: PYRIMIDINE;Pyrimidine series;Heterocycle-Pyrimidine series
• Mol File: 45588-79-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 224.323 °C at 760 mmHg
• Flash Point: 112.07 °C
• Appearance: /
• Density: 1.138 g/cm³
• Vapor Pressure: 0.092mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 7.46±0.29(Predicted)
• CAS DataBase Reference: 4-(AMINOMETHYL)-PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(AMINOMETHYL)-PYRIMIDINE(45588-79-2)
• EPA Substance Registry System: 4-(AMINOMETHYL)-PYRIMIDINE(45588-79-2)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 45588-79-2(Hazardous Substances Data)

Usage

General Description

4-(Aminomethyl)-pyrimidine is a chemical compound with the formula C5H6N4. It is a heterocyclic compound containing a pyrimidine ring, with an aminomethyl group attached to the carbon at position 4. 4-(AMINOMETHYL)-PYRIMIDINE is used in the synthesis of pharmaceutical drugs and agricultural chemicals. It is also used as a building block in organic synthesis to create various compounds with biological activity. 4-(Aminomethyl)-pyrimidine has potential applications in the development of new drugs and agrochemicals due to its versatile reactivity and ability to modify the properties of other compounds.

InChI:InChI=1/C5H7N3/c6-3-5-1-2-7-4-8-5/h1-2,4H,3,6H2

Upstream product

• 25746-87-6 acetal dimethylique du pyrimidine-4 carboxaldehyde 

Downstream Products

• 82298-80-4 N-Pyrimidin-4-ylmethyl-formamide 
• 676993-87-6 6-(3-chloro-phenylamino)-4-isopropyl-N-pyrimidin-4-ylmethyl-nicotinamide 
• 105918-10-3 3-[3-[N-(4-fluorobenzyl)-N-pyrid-2-ylamino]propylamino]-4-pyrimidin-4-ylmethylamino-1,2,5-thiadiazole-1-oxide 
• 530090-27-8 (Z)-2-{1-[2-chloro-4-(3-methyl-1H-pyrazol-1-yl)benzoyl]-4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene}-N-(pyrimidin-4-ylmethyl)acetamide 
• 1611472-75-3 8-(4-chlorophenyl)-N-(pyrimidin-4-ylmethyl)-1,6-naphthyridine-2-carboxamide 
• 1372590-12-9 3-{2-[methyl(methylsulfonyl)amino]phenyl}-11-oxo-N-(pyrimidin-4-ylmethyl)-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepine-7-carboxamide 
• 1316759-18-8 C₂₇H₂₆N₄O₂ 
• 1316759-08-6 4-[4-[2-[(3S)-3-hydroxyquinuclidin-3-yl]ethynyl]phenoxy]-N-(pyrimidin-4-ylmethyl)benzamide 
• 1254308-89-8 C₃₀H₂₉N₇O₂ 

Relevant articles and documents

1,2,3-TRIAZOLOAZINES ET AUTRES HETEROCYCLES AZOTES DERIVES D'AZINE-CARBOXALDEHYDES

α-(N)-azine-carboxaldehydes are convenient precursors of 1,2,3-triazoloazines.Through oxidative cyclisation of the corresponding hydrazones we have prepared the new 1,2,3-triazolopyridazine and 1,2,3-triazolopyrazine.Unlike the other azaindolizines these compounds are degraded by electrophiles. attempts to prepare imidazopyrimidine or derivatives have been carried out either from 4-aminomethylpyrimidine or from ethyl 2-(4-pyrimidinyl)propionate.