455901-40-3

Upstream product

• 455901-38-9 (4E)-1-[(4R)-2-oxo-4-benzyl(1,3-oxazolidin-3-yl)](3S,2R)-6-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-3-hydroxy-2-methylhex-4-en-1-one 
• 455901-50-5 (E)-(4R,5S)-8-(tert-Butyl-diphenyl-silanyloxy)-5-hydroxy-4-methyl-oct-6-en-1-yn-3-one 
• 455901-49-2 (E)-(2R,3S)-6-(tert-Butyl-diphenyl-silanyloxy)-3-hydroxy-2-methyl-hex-4-enoic acid methoxy-methyl-amide 
• 131380-48-8 (E)-4-(t-butyldiphenylsilyl)oxy-2-butenal 
• 455901-51-6 C₃₇H₆₀O₃Si₃ 
• 455901-39-0 (6E)-(3S,5S,4R)-8-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-4-methyloct-6-en-1-yne-3,5-diol 

Relevant academic research and scientific papers

A cascade cycloaddition strategy leading to the total synthesis of (-)-FR182877

A tandem transannular [4+2] cycloaddition strategy is presented for the synthesis of the class of natural products containing FR182877 (1) and hexacyclinic acid (2). As part of this program, a tandem transannular [4+2] cycloaddition reaction has been empl