4567-33-3

Usage

Uses

Used in Pharmaceutical Industry:
Neocnidilide is used as a neuroprotective agent for its potential in treating neurodegenerative diseases such as Alzheimer's and Parkinson's. Its antioxidant and anti-inflammatory properties contribute to the protection of nerve cells from damage and may slow the progression of these conditions.
Used in Cognitive Function Enhancement:
Neocnidilide is used as a cognitive enhancer to improve memory and cognitive function. Its potential to enhance these aspects is currently being investigated, indicating its possible use in applications related to cognitive health and performance.
Used in Research and Development:
Neocnidilide is used as a subject of research for further understanding its neuroprotective properties and exploring its potential applications in the treatment of neurological disorders. Ongoing studies aim to uncover more about its mechanisms of action and therapeutic potential.

InChI:InChI=1/C12H18O2/c1-2-3-8-11-9-6-4-5-7-10(9)12(13)14-11/h7,9,11H,2-6,8H2,1H3/t9-,11+/m1/s1

Upstream product

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• 948046-08-0 (1R,1'S)-1-(2'-bromocyclohex-2'-enyl)pentan-1-ol 
• 1265141-46-5 (1R,1'S)-1-(2'-bromocyclohex-2'-enyl)pentyl 2-chloroacetate 
• 948046-11-5 (S)-1-(2'-bromocyclohex-2'-enyl)pentan-1-one 
• 948046-12-6 (1S,1'S)-1-(2'-bromocyclohex-2'-enyl)pentan-1-ol 
• 110-62-3 pentanal 
• 17202-32-3 1,6-dibromocyclohex-1-ene 
• 75040-93-6 N-methyl-1-cyclohexene-1-carboxamide 
• 2550-47-2 ((3SR,3aSR,7aRS)-3-butyloctahydroisobenzofuran-1,1-diyl)dimethanol 

Relevant academic research and scientific papers

Total syntheses of (±)-cis- and (±)-trans-neocnidilides

Total syntheses of two antimicrobial natural products (±)-cis- neocnidilide and (±)-trans-neocnidilide starting from a readily preparable cyclohexa[b]-fused 5-oxabicyclo[2.1.1]hexane derivative are presented. The diastereomeric tetrahydrofuran tricarboxylate epimers obtained from a BF3·OEt2 promoted Grob-type fragmentation of the oxa-bicycle derivative were converted into title natural products by employing pyridinium dichromate/acetic anhydride mediated bis-oxidative cleavage reaction.

Synthesis and sensory evaluation of all stereoisomers of sedanolide

Synthesis and sensory evaluation of all stereoisomers of sedanolide (1) are described. The asymmetric synthesis was achieved with using the all stereoisomers of bromoalcohol (3) prepared by enzymatic resolution and inversion of the secondary alcohol. All

Pentacovalent Oxaphosphorane Chemistry in Organic Synthesis. 2. Total Syntheses of (+/-)-trans- and (+/-)-cis-Neocnidilides

Both (+/-)-trans- and (+/-)-cis-neocnidilides (1 and 2) have been synthesized via the route illustrated in Scheme III.The condensation of the 1,2λ5-oxaphospholene 5b with valeraldehyde produced the highly substituted phosphonates 12s and 12a, which were transformed via an intramolecular Wadsworth-Horner-Emmons olefination reaction to the title compounds.