457058-85-4Relevant academic research and scientific papers
Total synthesis of gambierol
Fuwa, Haruhiko,Sasaki, Makoto,Satake, Masayuki,Tachibana, Kazuo
, p. 2981 - 2984 (2002)
(Formula Represented) The first total synthesis of gambierol, a marine polycyclic ether toxin, has been achieved. The synthesis features the Pd(PPh3)4/CuCl/LiCl-promoted Stille coupling for the stereoselective construction of the sen
Total synthesis of (-)-gambierol
Fuwa, Haruhiko,Kainuma, Noriko,Tachibana, Kazuo,Sasaki, Makoto
, p. 14983 - 14992 (2007/10/03)
The first total synthesis of (-)-gambierol (1), a marine polycyclic ether toxin, has been achieved. Key features of the successful synthesis include (1) a convergent union of the ABC and EFGH ring fragments (5 and 6, respectively) via our developed B-alky
