457622-91-2

Upstream product

• 194149-76-3 (3R,8S,8aR)-8-ethyl-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 56613-80-0 D-2-phenylglycinol 
• 66757-48-0 methyl 4-formylhexanoate 
• 817574-26-8 (3R,8S,8aR)-8-ethyl-5-oxo-3-phenyl-6-(phenylsulfinyl)-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 

Downstream Products

• 457622-92-3 (3R,7R,8S,8aR)-7-[2-(ethoxycarbonyl)-1,3-dithiolan-2-yl]-8-ethyl-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 755759-01-4 methyl (3R,7R,8S,8aR)-8-ethyl-α-(1-methyl-2-indolyl)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine-7-acetate 
• 755759-23-0 (3R,7R,8S,8aR)-8-ethyl-7-[2-(2-indolyl)-1,3-dithiolan-2-yl]-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 755759-06-9 (3R,7S,8S,8aR)-8-ethyl-7-[2-(2-indolyl)-1,3-dithiolan-2-yl]-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 755759-22-9 methyl (3R,7R,8S,8aR)-8-ethyl-α-(2-indolyl)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine-7-acetate 
• 755759-16-1 methyl (3R,7R,8S,8aR)-8-ethyl-α-(2-indolyl)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine-7-acetate 
• 817574-40-6 (3R,7R,8S)-7-(1,3-dithian-2-yl)-8-ethyl-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 817573-54-9 (3R,7S,8S)-7-(1,3-dithian-2-yl)-8-ethyl-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 817573-58-3 (3R,7R,8S,8aR)-8-ethyl-5-oxo-3-phenyl-7-(2-phenyl-1,3-dithian-2-yl)-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 817574-41-7 (3R,7R,8S,8aR)-8-ethyl-5-oxo-3-phenyl-7-[bis(phenylthio)methyl]-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 817573-56-1 (3R,7S,8S,8aR)-8-ethyl-5-oxo-3-phenyl-7-[bis(phenylthio)methyl]-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 817573-86-7 (3R,7S,8S,8aR)-8-ethyl-7-(2-indolylmethyl)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 952686-31-6 C₂₄H₂₆N₂O₂ 
• 952686-29-2 C₂₄H₃₀N₂O 

Relevant academic research and scientific papers

Conjugate additions to phenylglycinol-derived unsaturated δ-lactams. Enantioselective synthesis of uleine alkaloids

The stereochemical outcome of the conjugate addition of a variety of stabilized nucleophiles (2-indoleacetic enolates and sulfur-stabilized anions) to the phenylglycinol-derived unsaturated lactams trans-2, cis-2, and its 8-ethyl-substituted analogue 10 i

Stereodivergent synthesis of enantiopure cis- and trans-3-ethyl-4-piperidineacetates

(Matrix presented) Starting from a common chiral bicyclic lactam 11, enantiopure trans-or Cis-3-ethyl-4-piperidineacetate derivatives are obtained by conjugate addition of an enolate or a cuprate to the unsaturated lactams 12 or 18, respectively.