45765-25-1Relevant articles and documents
Copper-Catalyzed Three-Component Tandem Cyclization for One-Pot Synthesis of 1,4-Benzothiazines
Chu, Jing-Jing,Hu, Bo-Lun,Liao, Zhi-Yong,Zhang, Xing-Guo
, p. 8647 - 8652 (2016)
A copper-catalyzed three-component tandem reaction has been developed for the convenient and practical synthesis of 1,4-benzothiazines. A variety of terminal alkynes and 2-iodo/bromophenyl isothiocyanates underwent this one-pot cyclization with aqueous ammonia to afford 1,4-benzothiazines in moderate to good yields.
Development of S-Substituted Thioisothioureas as Efficient Hydropersulfide Precursors
Khodade, Vinayak S.,Toscano, John P.
, p. 17333 - 17337 (2019/01/04)
Because of their inherent instability, hydropersulfides (RSSH) must be generated in situ using precursors, but very few physiologically useful RSSH precursors have been developed to date. In this work, we report the design, synthesis, and evaluation of novel S-substituted thiosiothioureas as RSSH precursors. These water-soluble precursors show efficient and controllable release of RSSH under physiological conditions.
Efficient iron(III) porphyrins-catalyzed oxidation of guanidoximes to cyanamides in ionic liquids
Kumari, Pratibha,Nagpal, Ritika,Chauhan, Prashant,Yatindranath, Vinith,Chauhan, Shive M. S.
, p. 13 - 18 (2015/03/30)
Water soluble iron(III) porphyrins immobilized in imidazolium ionic liquids serve as an effective catalyst for the H2O2 mediated oxidation of guanidoximes to selectively give corresponding cyanamides in good yields. The use of ionic liquid with non-coordinating counter anion PF6 affords the product in high yield by facilitating the formation of anionic iron peroxo intermediate. [Figure not available: see fulltext.]