622-34-4

Basic information

• Product Name: phenylcyanamide
• Synonyms: phenylcyanamide;Anilino cyanide;Carbanilonitrile;Phenylcarbamonitrile;Phenylcyanoamine
• CAS NO: 622-34-4
• Molecular Formula: C₇H₆N₂
• Molecular Weight: 118.13594
• EINECS: 210-729-8
• Mol File: 622-34-4.mol
• Article Data: 79

Chemical Properties

• Melting Point: 44-46 °C
• Boiling Point: 191.3°C at 760 mmHg
• Flash Point: 69.5°C
• Appearance: /
• Density: 1.155g/cm³
• Vapor Pressure: 0.517mmHg at 25°C
• Refractive Index: 1.616
• PKA: -2.31±0.38(Predicted)
• CAS DataBase Reference: phenylcyanamide(CAS DataBase Reference)
• NIST Chemistry Reference: phenylcyanamide(622-34-4)
• EPA Substance Registry System: phenylcyanamide(622-34-4)

Safety Data

• Hazardous Substances Data: 622-34-4(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 46, p. 1045, 1981 DOI: 10.1021/jo00318a049

InChI:InChI=1/C7H6N2/c8-6-9-7-4-2-1-3-5-7/h1-5,9H

Upstream product

• 5378-52-9 phenyl-1H-tetrazole 
• 103-72-0 phenyl isothiocyanate 
• 103-85-5 monophenylthiourea 
• 64-17-5 ethanol 
• 6919-35-3 N-hydroxy-N'-phenyl-thiourea 
• 75307-67-4 2,2-dimethyl-[1,3]dioxane-4,5,6-trione-5-phenylhydrazone 
• 56476-95-0 2-phenyl-2H-tetrazole 
• 6017-59-0 3-methyl-4-phenylhydrazonoisoxazol-5-one 
• 7758-99-8 copper(II) sulfate 
• 546-67-8 lead(IV) tetraacetate 
• 142-71-2 copper diacetate 
• 64-19-7 acetic acid 
• 100-44-7 benzyl chloride 
• 36289-36-8 N-cyanoimidazole 

Downstream Products

• 17823-27-7 2-phenylaminothiazol-4-one 
• 57469-23-5 N-cyano-N-phenylbenzenesulfonamide 
• 55305-43-6 N-cyano-N-phenyl-p-toluenesulfonamide 
• 98997-21-8 N-phenylcarbamimidoyl-glycine 
• 3305-89-3 Kohlensaeurephenylester-imid-phenylcyanamid 
• 56014-13-2 1,N,N'-triphenyl-1,5(7)-dihydro-4λ⁴-[1,2,4]thiadiazolo[5,1-e][1,2,4]thiadiazole-2,6-diamine 
• 59236-39-4 N-(3-anilino-[1,2,4]thiadiazol-5-yl)-N,N'-diphenyl-guanidine 
• 56014-25-6 N⁶-phenyl-1,N²-di-p-tolyl-1,5(7)-dihydro-4λ⁴-[1,2,4]thiadiazolo[5,1-e][1,2,4]thiadiazole-2,6-diamine 
• 114688-22-1 2-[1-Amino-1-phenylamino-meth-(Z)-ylidene]-3-oxo-butyric acid ethyl ester 
• 114688-22-1 2-[1-Amino-1-phenylamino-meth-(E)-ylidene]-3-oxo-butyric acid ethyl ester 
• 172293-27-5 acetyl(ethoxycarbonyl)ketene (N-benzoyl)aminal 
• 114688-23-2 (Z)-3-Amino-2-benzoyl-3-phenylamino-acrylic acid ethyl ester 
• 114688-23-2 (E)-3-Amino-2-benzoyl-3-phenylamino-acrylic acid ethyl ester 
• 114688-21-0 2-(Amino-phenylamino-methylene)-1,3-diphenyl-propane-1,3-dione 

Relevant articles and documents

The Photolysis of 2-Phenyltetrazole

The photolysis of 2-phenyltetrazole (1) in benzene yields phenylcyanamide (27percent) and the phenylhydrazone of o-aminobenzoyl cyanide (53percent) whose structure was determined by X-ray crystal structure analysis.

New compounds: Potential antituberculous agents I: Alkylaryl 4-arylformamidinothiosemicarbazones

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Synthesis of nitriles via the iodine-mediated dehydrosulfurization of thioamides

A simple general method for the synthesis of nitriles using the inexpensive and easy to handle iodine (I2) is described herein. The reaction of thioamides with I2 in the presence of triethylamine at room temperature under aerobic conditions afforded various nitriles bearing aryl, vinyl, and alkyl groups in good-to-excellent yields. This method was also effective for conversion from thioureas to cyanamides.

SO2F2-Mediated one-pot cascade process for transformation of aldehydes (RCHO) to cyanamides (RNHCN)

A simple, mild and practical cascade process for the direct conversion of aldehydes to cyanamides was developed featuring a wide substrate scope and great functional group tolerability. This method allows for transformations of readily available, inexpensive, and abundant aldehydes to highly valuable cyanamides in a pot, atom, and step-economical manner with a green nitrogen source. This protocol will serve as a robust tool for the installation of the cyanamide moiety in various complicated molecules.