Cas 458151-58-1,2-(3-(2,5-dioxo-3,4-diphenyl-2,5-dihydro-1H-pyrrol-1-yl)-2,6-dioxopiperidin-1-yl)-N,N-dimethylethanamine hydrochloride

458151-58-1

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Basic information

Product Name: 2-(3-(2,5-dioxo-3,4-diphenyl-2,5-dihydro-1H-pyrrol-1-yl)-2,6-dioxopiperidin-1-yl)-N,N-dimethylethanamine hydrochloride
Synonyms: 2-(3-(2,5-dioxo-3,4-diphenyl-2,5-dihydro-1H-pyrrol-1-yl)-2,6-dioxopiperidin-1-yl)-N,N-dimethylethanamine hydrochloride
CAS NO:458151-58-1
Molecular Formula:
Molecular Weight: 467.952
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 2-(3-(2,5-dioxo-3,4-diphenyl-2,5-dihydro-1H-pyrrol-1-yl)-2,6-dioxopiperidin-1-yl)-N,N-dimethylethanamine hydrochloride(CAS DataBase Reference)
NIST Chemistry Reference: 2-(3-(2,5-dioxo-3,4-diphenyl-2,5-dihydro-1H-pyrrol-1-yl)-2,6-dioxopiperidin-1-yl)-N,N-dimethylethanamine hydrochloride(458151-58-1)
EPA Substance Registry System: 2-(3-(2,5-dioxo-3,4-diphenyl-2,5-dihydro-1H-pyrrol-1-yl)-2,6-dioxopiperidin-1-yl)-N,N-dimethylethanamine hydrochloride(458151-58-1)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 458151-58-1(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 458151-58-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,8,1,5 and 1 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 458151-58:
(8*4)+(7*5)+(6*8)+(5*1)+(4*5)+(3*1)+(2*5)+(1*8)=161
161 % 10 = 1
So 458151-58-1 is a valid CAS Registry Number.

458151-58-1Upstream product

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458151-58-1Relevant academic research and scientific papers

Discovering a new analogue of thalidomide which may be used as a potent modulator of TNF-α production

Brana, Miguel Fernandez,Acero, Nuria,Anorbe, Loreto,Mingarro, Dolores Munoz,Llinares, Francisco,Dominguez, Gema

experimental part, p. 3533 - 3542 (2009/12/04)

A new series of imide derivatives related to thalidomide were synthesized and evaluated as modulators of TNF-α production. These derivatives enhance TNF-α production using human leukemia HL-60 cells induced with 12-O-tetradecanoylphorbol 13-acetate (TPA), while inhibiting TNF-α production induced with okadaic acid (OA) in the same cell line. The diphenylmaleimide derivative 2f, was found to be the most active product, producing a strong modulation of the cytokine level.

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