4583-87-3Relevant academic research and scientific papers
Copper catalyzed C-N bond formation/C-H activation: Synthesis of aryl 4H-3,1-benzoxazin-4-ones
Munusamy, Sathishkumar,Venkatesan, Sathesh,Sathiyanarayanan, Kulathu Iyer
, p. 203 - 205 (2015)
We have developed a practical and efficient synthesis of 2-phenyl-4H-benzo[d][1,3]oxazine-4-one derivatives through copper catalyzed tandem reaction of 2-iodobenzoic acid with arylmethanamines under aerobic conditions. Compared to the literature methods toward the synthesis of 2-phenyl-4H-benzo[d][1,3]oxazine-4-one, the synthetic method reported in this Letter has broad substrate scope, mild reaction condition, and uses an inexpensive catalyst.
