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(-)-Elema-1,3,11(13)-trien-12-al is a naturally occurring sesquiterpene compound, characterized by its unique tricyclic structure and the presence of a carbonyl group at the C-12 position. This organic molecule is derived from elemol, a bioactive compound found in various plants, particularly in the genus Curcuma. It exhibits a range of biological activities, including anti-inflammatory, antitumor, and antimicrobial properties. The compound's stereochemistry is crucial for its biological activity, with the (-)-enantiomer being the most active. Its chemical structure features a 12-aldehyde functional group, which is responsible for its reactivity and potential applications in the synthesis of other bioactive compounds. The compound's name reflects its origin from elemol and its specific carbon skeleton, highlighting the positions of the double bonds and the aldehyde group.

4584-28-5

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4584-28-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4584-28-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,8 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4584-28:
(6*4)+(5*5)+(4*8)+(3*4)+(2*2)+(1*8)=105
105 % 10 = 5
So 4584-28-5 is a valid CAS Registry Number.

4584-28-5Relevant academic research and scientific papers

HIRSUTINOLIDES FROM SOUTH AFRICAN VERNONIA SPECIES

Bohlmann, Ferdinand,Ates, Nezhun,Jakupovic, Jasmin

, p. 1159 - 1162 (1983)

The investigation of four South African Vernonia species afforded, in addition to known compounds, six ketohirsutinolides with different oxygen functions at C-8 and C-13, respectively.Furthermore, an eremantholide was present, which was the 16-epimer of a known compound and two sesquiterpene aldehydes were isolated. - Key Word Index: Vernonia glabra var. glabra; V. poskeana var. poskeana; V. poskeana var. chlorolepis; V. neocorymbosa; Compositae; sesquiterpene lactones; hirsutinolides; sesquiterpene aldehydes.

Rational design, synthesis and biological evaluation of novel derivatives based on in vivo metabolism of natural product β-elemene

Bai, Renren,Jie, Xiaokang,Salgado, Eric,Sun, Jian,Zhu, Yao,Pickel, Thomas,Xie, Yuanyuan,Chen, Jichao,Xu, Jinyi

, p. 905 - 912 (2018/07/03)

Background: Natural products have been an exemplary source of new drugs as they have served as direct or indirect precursors for many currently available medicines. The natural product β -elemene has been used clinically in the treatment of various cancer

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