458561-78-9Relevant academic research and scientific papers
Synthesis of suspected carcinogenic metabolites of 7H-benzo[c]fluorene, a coal tar component implicated in causation of lung tumors.
Wang, Ji-Quan,Weyand, Eric H,Harvey, Ronald G
, p. 6216 - 6219 (2002)
High incidences of lung tumors were observed in mice fed coal tar in their diet. The principal component of tar that gives rise to DNA-bound adducts in mouse lung was identified as 7H-benzo[c]fluorene (BcF). We now report the synthesis of suspected active
