73022-40-9

Basic information

• Product Name: 2-(Bromomethyl)-6-methoxynaphthalene
• Synonyms: 2-(Bromomethyl)-6-methoxynaphthalene
• CAS NO: 73022-40-9
• Molecular Formula: C₁₂H₁₁BrO
• Molecular Weight: 251.11914
• Mol File: 73022-40-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(Bromomethyl)-6-methoxynaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Bromomethyl)-6-methoxynaphthalene(73022-40-9)
• EPA Substance Registry System: 2-(Bromomethyl)-6-methoxynaphthalene(73022-40-9)

Safety Data

• Hazardous Substances Data: 73022-40-9(Hazardous Substances Data)

Usage

General Description

2-(Bromomethyl)-6-methoxynaphthalene is a chemical compound that consists of a naphthalene core with a bromomethyl group and a methoxy group attached at specific positions. It has a molecular formula of C11H11BrO and a molecular weight of 239.11 g/mol. 2-(Bromomethyl)-6-methoxynaphthalene is commonly used as a building block in organic synthesis and can be utilized in the production of various pharmaceuticals and agrochemicals. The bromomethyl group makes the compound reactive and useful in the synthesis of complex organic molecules, while the methoxy group provides increased stability and can alter the compound's biological activity. Due to its chemical structure, 2-(Bromomethyl)-6-methoxynaphthalene should be handled and used in accordance with proper safety procedures and regulations.

Upstream product

• 26386-94-7 2-methyl-6-methoxynaphthalene 
• 93-00-5 Bronner acid 
• 92190-49-3 (6-methoxynaphthalene-2-yl)methyl acetate 
• 3453-33-6 6-methoxynaphthalene-2-carbaldehyde 
• 3900-45-6 6-methoxy-2-acetylnaphthalene 
• 60201-22-1 (6-methoxy-2-naphthyl)methanol 
• 2471-70-7 2-methoxy-6-naphthoic acid 

Downstream Products

• 71056-96-7 2-(6-methoxynaphthalen-2-yl)acetonitrile 
• 458561-78-9 2-[(2-methoxy-6-naphthyl)methyl]cyclohexanone 
• 42924-53-8 nabumetone 
• 1477473-41-8 2-((6-methoxynaphthalen-2-yl)methyl)-2-(1-phenylbut-3-en-1-yl)malononitrile 
• 1477473-71-4 2-allyl-2-(2-(6-methoxynaphthalen-2-yl)-1-phenylethyl)malononitrile 

Relevant articles and documents

Using fluorogenic probes for the investigation of selective biomass degradation by fungi

A library of fifteen commercially purchased and synthetic fluorogenic probes was employed for the investigation of biomass degradation using extracts of white-rot fungi. These probes were selected or designed to mimic the dominant linkages in celluloses, hemicelluloses, and lignin, the three most abundant polymers found in biomass. The results show that white-rot fungi display a high preference for cleaving mannose- and glucose-based probes, which mimic hemicelluloses. Low degrees of cleavages were noted for xylose- and cellobiose-based probes. No cleavages were observed for probes that mimic the linkages in lignin. Overall, these discoveries prove that it is possible to employ fungi for selective degradation or release of hemicelluloses from biomass.

NAPTHTHALENE DERIVATIVES WHICH INHIBIT THE CYTOKINE OR BIOLOGICAL ACTIVITY OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF)

Where Y, R1-R8 and R101-R108 are as defined in the specification. Compounds of formula (II) and methods of inhibiting the cytokine or biological activity of Macrophage Migrating Inhibitory Factor (MIF) comprising contacting MIF with a compound of formula (I) are provided. The invention also relates to methods of treating diseases or conditions where MIF cytokine or biological activity is implicated comprising administration of compounds of formula (I), either alone or as part of a combination therapy.

Enantioselective hydrolysis of naproxen ethyl ester catalyzed by monoclonal antibodies

This report described that a hapten of racemic phosphonate 3 designed as the mimic of the transition state of hydrolysis of naproxen ethyl ester was successfully synthesized from easily available 2-acetyl-6-methoxy-naphthalene 5. Then BALB/C mice were immunized and one of the monoclonal catalytic antibodies, N116-27, which enantioselectively accelerated the hydrolysis of the R-(-)-naproxen ethyl ester was given. The Michaelis-Menton parameter for the catalyzed reaction was KM=6.67 mM and kcat/kuncat=5.8×104. This enantioselective result was explained by the fact that the R-isomer of rac-hapten was more immunogenic than the S-isomer.