458563-96-7Relevant academic research and scientific papers
Sidearm effect: Improvement of the enantiomeric excess in the asymmetric Michael addition of indoles to alkylidene malonates
Zhou, Jian,Tang, Yong
, p. 9030 - 9031 (2002)
A pseudo-C3-trisoxazoline was designed and synthesized. The improvement of the traditional bisoxazoline into a novel trisoxazoline by a sidearm approach resulted in highly catalytic enantioselective Michael addition of indoles to alkylidene mal
Modification of pseudo-C3-symmetric trisoxazoline and its application to the Friedel-Crafts alkylation of indoles and pyrrole with alkylidene malonates
Zhou, You-Yun,Sun, Xiu-Li,Zhu, Ben-Hu,Zheng, Jun-Cheng,Zhou, Jiao-Long,Tang, Yong
supporting information; experimental part, p. 935 - 938 (2011/06/17)
New pseudo-C3-symmetric hetero-trisoxazoline can be easily prepared on a gram scale in good yield. Its combination with copper(II) triflate exhibits high enantiomeric induction in the asymmetric Friedel-Crafts alkylation between indoles and alk
N,N′-Dioxide-scandium(III) complex catalyzed highly enantioselective Friedel-Crafts alkylation of indole to alkylidene malonates
Liu, Yanling,Zhou, Xin,Shang, Deju,Liu, Xiaohua,Feng, Xiaoming
experimental part, p. 1447 - 1457 (2010/04/02)
A highly efficient enantioselective Friedel-Crafts alkylation of indoles with alkylidene malonates has been developed using chiral N,N′-dioxide L4-scandium(III) complex as the catalyst, giving the corresponding products in high yields with excellent enant
Methods for synthesis of 3-amino-1-arylpropyl indoles
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Page/Page column 12-13, (2008/06/13)
A method comprising: hydrogenating an indole propionamide compound of formula h with vitride, to form an aminopropyl indole compound of formula i wherein m, Ar, R1 and R2 are as defined herein. The compounds prepared by the method of
