45879-15-0

Upstream product

• 551-93-9 2-aminoacetophenone 
• 577-59-3 2-acetylnitrobenzene 

Downstream Products

• 117783-04-7 3-(2-acetylphenylhydrazone)-1,1,1-trifluoro-2,4-pentane dione 
• 117783-03-6 2-(2-acetylphenylhydrazone)-5,5-dimethyl-1,3-cyclohexane dione 
• 482-89-3 1H,1H'-2,2'-Biindolylidene-3,3'-dione 
• 123228-48-8 2-(2-Acetyl-phenyl)-6-amino-2H-benzotriazole-4-carboxylic acid 
• 38377-09-2 2-(2-acetylphenylhydrazone)-1-phenyl-1,3-butane dione 

Relevant academic research and scientific papers

2,2-Disubstituted-1,2-dihydro-3H-indol-3-ones by Base- and Thermal-induced Cyclisations of o-Azidophenyl s-Alkyl Ketones and o-Azidobenzoyl Esters

o-Azidophenyl s-alkyl ketones in ethanolic potassium hydroxide at room temperature undergo loss of nitrogen and cyclisation to 2,2-dialkyl-1,2-dihydro-3H-indol-3-ones in high yield.Kinetic data (E(act.) 62.4 and 71.6 kJ mol-1, respectively) obtained for the o-azidophenylisopropyl and o-azidophenylcyclohexyl ketones support an assisted nitrogen loss from the azide via the enolate ion, rather than a nitrene reaction. 1,2-Dihydro-3H-indol-3-ones, along with in some cases 2,1-benzisoxazoles, have been obtained by the thermolysis and spray vacuum pyrolysis of other o-azidophenyl alkyl ketones, diethyl o-azidobenzoyl malonate, and ethyl o- azidobenzoyl(phenyl)acetate.