459133-81-4

Upstream product

• 459133-66-5 5-bromo-3-iodo-1H-indazole 
• 53857-57-1 5-bromo-1H-indazole 
• 24424-99-5 di-tert-butyl dicarbonate 
• 55022-46-3 4-methyl-N-prop-2-ynylbenzenesulfonamide 
• 459133-68-7 tert-butyl 5-bromo-3-iodo-1H-indazole-1-carboxylate 

Relevant academic research and scientific papers

Sequential Sonogashira and Suzuki cross-coupling reactions in the indole and indazole series

3-Iodoindoles, 5-bromo-3-iodoindoles and 5-bromo-3-iodoindazoles have been studied with respect to their reactivity and selectivity in palladium catalyzed Sonogashira and Suzuki cross-coupling reactions. As a result, sequential Sonogashira-Sonogashira, So

Sonogashira cross-coupling reaction of 3-iodoindazoles with various terminal alkynes: A mild and flexible strategy to design 2-aza tryptamines

This paper describes a Sonogashira-type cross-coupling reaction of 3-iodoindazoles with various terminal alkynes as a general route to 3-alkynylindazoles. The coupling reaction is illustrated by the preparation of new indazolylpropiolic or propargylic derivatives. Scope and limitation of the method are outlined.