459216-80-9

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 30020-68-9 3-phenyl-1-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)prop-2-en-1-one 
• 89-25-8 edaravone 
• 2700-22-3 Benzylidenemalononitrile 
• 128256-47-3 4-(1-iminoethyl)-3-methyl-1-phenyl-2-pyrazolin-5-one 

Downstream Products

• 459217-36-8 7-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-5-phenylpyrido[2,3-d]pyrimidine-2,4(1H,3H)-dithione 
• 459216-86-5 2-(ethoxymethyleneamino)-6-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-4-phenylpyridine-3-carbonitrile 
• 459217-45-9 4-amino-2-trichloromethyl-7-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-5-phenylpyrido[2,3-d]pyrimidine 
• 459217-23-3 2-amino-6-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-4-phenylpyridin-3-carboxamide 

Relevant academic research and scientific papers

Synthesis and biological activity of some new pyridines, pyrans, and indazoles containing pyrazolone moiety

Cyclocondensation reactions of 3-phenyl-1-(3-methyl-5-oxo-1-phenyl-2- pyrazolin-4-yl) prop-2-en-1-one (2) with active methylene reagents such as ethyl cyanoacetate, malononitrile, ethyl acetoacetate, and acetoacetanilide afforded pyrazolinyl pyridine deri

Synthesis and reactions of 2-amino-6-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-4-phenylpyridine-3- carbonitrile

2-Amino-6-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-4-phenylpyridine-3- carbonitrile (1) obtained by the reaction of 4-(1-iminoethyl)-3-methyl-1-phenyl-2-pyrazolin-5-one with benzylidenemalononitrile, was reacted with triethyl orthoformate followed by hydrazine hydrate, acetic anhydride, acetyl chloride, alkyl halides, benzoyl chloride, sulphuric acid followed by formamide, phenyl isothiocyanate, carbon disulphide followed by ethyl iodide, formamide, trichloroacetonitrile, nitrous acid, giving new oxopyrazolinylpyridines (2,3,5,6,8,9,10) and related pyridopyrimidines (11-17) and pyridotriazine (18).