459424-72-7

Basic information

• Product Name: 1-Iodo-2,3,4-trifluorobenzene
• Synonyms: 4-Iodo-1,2,3-trifluorobenzene;Benzene, 1,2,3-trifluoro-4-iodo-
• CAS NO: 459424-72-7
• Molecular Formula: C₆H₂F₃I
• Molecular Weight: 257.9797596
• Product Categories: Fluorine series
• Mol File: 459424-72-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 182.4°C at 760 mmHg
• Flash Point: 67.7°C
• Appearance: /
• Density: 2.078g/cm³
• Vapor Pressure: 1.11mmHg at 25°C
• Refractive Index: 1.543
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 1-Iodo-2,3,4-trifluorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Iodo-2,3,4-trifluorobenzene(459424-72-7)
• EPA Substance Registry System: 1-Iodo-2,3,4-trifluorobenzene(459424-72-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 459424-72-7(Hazardous Substances Data)

Usage

General Description

1-Iodo-2,3,4-trifluorobenzene is a chemical compound with the molecular formula C6H3F3I. It is a derivative of benzene that is substituted with three fluorine atoms and one iodine atom. 1-Iodo-2,3,4-trifluorobenzene is commonly used as a building block in organic chemistry and can be used in the synthesis of various pharmaceuticals and agrochemicals. It is a colorless liquid with a strong, pungent odor and is considered to be moderately toxic. 1-Iodo-2,3,4-trifluorobenzene is also known for its use in the production of liquid crystal materials, which are used in electronic displays and other applications.

InChI:InChI=1/C6H2F3I/c7-3-1-2-4(10)6(9)5(3)8/h1-2H

Upstream product

• 176317-02-5 1-bromo-2,3,4-trifluorobenzene 
• 1489-53-8 1,2,3-trifluorobenzene 

Downstream Products

• 1097626-95-3 2,3,4-trifluoro-5-iodobenzaldehyde 
• 203916-59-0 2,3,4-trifluoro-5-iodobenzoic acid 
• 459425-36-6 2,3,4-trifluoro-1,5-diiodobenzene 

Relevant articles and documents

TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS

The present invention relates to tricyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthama, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases. (I)

CHROMAN DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE COMPOUND

The present invention relates to a liquid crystal compound which has negative dielectric anisotropy and a large absolute value thereof; and a liquid crystal display element which contains the compound as a constituent element and has a negative value of dielectric anisotropy in the vertical alignment mode, IPS, or the like. The liquid-crystal display element has a structure including a pair of substrates and a liquid crystal sandwiched therebetween, and includes at least an alignment control layer, a transparent electrode, and a polarizing plate, in which the liquid crystal includes at least one compound having a partial structure represented by general formula (A): (wherein W1 and W2 each independently represents fluorine, chlorine, -CF3, -CF2H, -OCF3, or -OCF2H) and has negative dielectric anistropy.

Synthesis and mesomorphic properties of some liquid crystals with 2,3,5,6-tetrafluorophenylene unit

Nine fluorosubstituted liquid crystals have been synthesized and their mesomorphic properties have been studied by texture observation in a polarizing microscope and confirmed by DSC. They show enantiotropic smectic A and nematic phases. The effect of ter