459448-36-3

Upstream product

• 459448-35-2 [3-(4-Phenylpiperazin-1-ylmethyl)-1H-indol-2-yl]-methanol 
• 92-54-6 4-phenyl-1-piperazine 
• 18450-27-6 ethyl 3-formyl-1H-indole-2-carboxylate 
• 459448-16-9 Ethyl 3-(4-phenylpiperazin-1-ylmethyl)-1H-indole-2-carboxylate 

Relevant academic research and scientific papers

Phenylpiperazinylmethylindolecarboxylates and derivatives as selective D(4)-ligands.

Novel phenylpiperazinylmethylindolecarboxylates were synthesized for evaluation as potential D(4)-ligands. Test compounds showed high affinity for the human dopamine D(4) receptor and great selectivity over the other receptor subtypes. Intrinsic effects of indole derivatives, which indicated most promising binding properties, were investigated in a mitogenesis assay.