459457-06-8

Basic information

• Product Name: N-(2-hydroxy-1-hydroxymethyl-propyl)-N-(2-iodo-ethyl)-4-methyl-benzenesulfonamide
• CAS NO: 459457-06-8
• Molecular Weight: 413.277
• Mol File: 459457-06-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-hydroxy-1-hydroxymethyl-propyl)-N-(2-iodo-ethyl)-4-methyl-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-hydroxy-1-hydroxymethyl-propyl)-N-(2-iodo-ethyl)-4-methyl-benzenesulfonamide(459457-06-8)
• EPA Substance Registry System: N-(2-hydroxy-1-hydroxymethyl-propyl)-N-(2-iodo-ethyl)-4-methyl-benzenesulfonamide(459457-06-8)

Safety Data

• Hazardous Substances Data: 459457-06-8(Hazardous Substances Data)

Upstream product

• 459457-02-4 4-Methyl-N-((4R,5R)-2,2,4-trimethyl-[1,3]dioxan-5-yl)-benzenesulfonamide 
• 459457-04-6 N-(2-hydroxy-ethyl)-4-methyl-N-(2,2,4-trimethyl-[1,3]dioxan-5-yl)-benzenesulfonamide 
• 459457-03-5 N-allyl-4-methyl-N-(2,2,4-trimethyl-[1,3]dioxan-5-yl)-benzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 43188-53-0 (2S,3R)-methyl-N-(4-methylphenylsulfonyl)-3-hydroxy-2-aminobutanoate 
• 34235-88-6 (2S,3S)-3-hydroxy-2-(4-methylphenylsulfonamido)butanoic acid 
• 459457-05-7 N-(2-iodo-ethyl)-4-methyl-N-(2,2,4-trimethyl-[1,3]dioxan-5-yl)-benzenesulfonamide 

Downstream Products

• 681236-64-6 (2S,3R)-3-hydroxy-3-methylpyrrolidine-2-carboxylic acid 
• 459457-15-9 (2R,3R)-2-hydroxymethyl-3-methyl-1-(toluene-4-sulfonyl)pyrrolidin-3-ol 
• 459457-14-8 N-(1-hydroxymethyl-2-oxo-propyl)-N-(2-iodo-ethyl)-4-methyl-benzenesulfonamide 
• 459457-08-0 N-[1-(tert-butyl-diphenyl-silanyloxymethyl)-2-oxo-propyl]-N-(2-iodo-ethyl)-4-methyl-benzenesulfonamide 
• 459457-07-9 N-[1-(tert-butyl-diphenyl-silanyloxymethyl)-2-hydroxy-propyl]-N-(2-iodo-ethyl)-4-methyl-benzenesulfonamide 
• 459457-11-5 N-(2-hydroxy-1-trityloxymethyl-propyl)-N-(2-iodo-ethyl)-4-methyl-benzenesulfonamide 

Relevant articles and documents

Synthetic studies on polyoxypeptins: Stereoselective synthesis of (2S,3R)-3-hydroxy-3-methylproline using SmI2-mediated cyclization

Stereoselective synthesis of (2S,3R)-3-hydroxy-3-methylproline (3), a component of polyoxypeptins, has been achieved by use of SmI2-mediated diastereoselective cyclization reaction as a key step.