459457-15-9

Basic information

• Product Name: (2R,3R)-2-hydroxymethyl-3-methyl-1-(toluene-4-sulfonyl)pyrrolidin-3-ol
• Synonyms: (2R,3R)-2-hydroxymethyl-3-methyl-1-(toluene-4-sulfonyl)pyrrolidin-3-ol
• CAS NO: 459457-15-9
• Molecular Weight: 285.364
• Mol File: 459457-15-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R,3R)-2-hydroxymethyl-3-methyl-1-(toluene-4-sulfonyl)pyrrolidin-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-2-hydroxymethyl-3-methyl-1-(toluene-4-sulfonyl)pyrrolidin-3-ol(459457-15-9)
• EPA Substance Registry System: (2R,3R)-2-hydroxymethyl-3-methyl-1-(toluene-4-sulfonyl)pyrrolidin-3-ol(459457-15-9)

Safety Data

• Hazardous Substances Data: 459457-15-9(Hazardous Substances Data)

Upstream product

• 459457-07-9 N-[1-(tert-butyl-diphenyl-silanyloxymethyl)-2-hydroxy-propyl]-N-(2-iodo-ethyl)-4-methyl-benzenesulfonamide 
• 459457-08-0 N-[1-(tert-butyl-diphenyl-silanyloxymethyl)-2-oxo-propyl]-N-(2-iodo-ethyl)-4-methyl-benzenesulfonamide 
• 459457-05-7 N-(2-iodo-ethyl)-4-methyl-N-(2,2,4-trimethyl-[1,3]dioxan-5-yl)-benzenesulfonamide 
• 459457-04-6 N-(2-hydroxy-ethyl)-4-methyl-N-(2,2,4-trimethyl-[1,3]dioxan-5-yl)-benzenesulfonamide 
• 459457-06-8 N-(2-hydroxy-1-hydroxymethyl-propyl)-N-(2-iodo-ethyl)-4-methyl-benzenesulfonamide 
• 459457-03-5 N-allyl-4-methyl-N-(2,2,4-trimethyl-[1,3]dioxan-5-yl)-benzenesulfonamide 
• 459457-02-4 4-Methyl-N-((4R,5R)-2,2,4-trimethyl-[1,3]dioxan-5-yl)-benzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 43188-53-0 (2S,3R)-methyl-N-(4-methylphenylsulfonyl)-3-hydroxy-2-aminobutanoate 
• 34235-88-6 (2S,3S)-3-hydroxy-2-(4-methylphenylsulfonamido)butanoic acid 
• 944413-16-5 4-methyl-N-(3-oxobutyl)-N-(2-oxoethyl)benzenesulfonamide 
• 459457-14-8 N-(1-hydroxymethyl-2-oxo-propyl)-N-(2-iodo-ethyl)-4-methyl-benzenesulfonamide 

Downstream Products

• 681236-64-6 (2S,3R)-3-hydroxy-3-methylpyrrolidine-2-carboxylic acid 

Relevant articles and documents

Organocatalytic synthesis of (2S,3R)-3-hydroxy-3-methyl-proline (OHMePro), a component of polyoxypeptins, and relatives using OHMePro itself as a catalyst

An efficient synthesis of (2S,3R)-3-hydroxy-3-methylproline (OHMePro), a component of polyoxypeptins, and relatives was achieved, in which an intramolecular asymmetric aldol reaction of the ketoaldehyde using OHMePro itself as an organocatalyst constitute