45977-26-2

Basic information

• Product Name: 9-Aza-1-methyl-bicyclo[3.3.1]nonan-3-one
• Synonyms: 9-Aza-1-methyl-bicyclo[3.3.1]nonan-3-one
• CAS NO: 45977-26-2
• Molecular Formula: C9H15NO
• Molecular Weight: 0
• Mol File: 45977-26-2.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 9-Aza-1-methyl-bicyclo[3.3.1]nonan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 9-Aza-1-methyl-bicyclo[3.3.1]nonan-3-one(45977-26-2)
• EPA Substance Registry System: 9-Aza-1-methyl-bicyclo[3.3.1]nonan-3-one(45977-26-2)

Safety Data

• Hazardous Substances Data: 45977-26-2(Hazardous Substances Data)

Upstream product

• 21889-88-3 hept-6-en-2-one 
• 542-05-2 acetonedicarboxylic acid 
• 505-03-3 5-oxohexanal 
• 1151797-19-1 C₁₀H₁₃NO₂ 
• 84002-79-9 3-methyl-2,7-cyclooctadienone 
• 35242-04-7 cis,cis-2,7-cyclooctadienone 
• 292045-89-7 N-methoxy-N-methyl-2-(10a-methyl-1,3,4,9,9a,10a-hexahydro-2H,4bH-10-oxa-4a-aza-indeno[1,2-a]inden-4-yl)-acetamide 
• 292045-88-6 N-methoxy-N-methyl-2-(10a-methyl-1,2,3,9,9a,10a-hexahydro-4bH-10-oxa-4a-aza-indeno[1,2-a]inden-4-ylidene)-acetamide 
• 263241-27-6 (1S,3R,5R,SR)-1-(p-tolylsulfinylmethyl)-10-oxa-9-azatricyclo[3.3.1.1^3,9]decane 
• 263241-26-5 (2S,SR)-2-allyl-N-hydroxy-2-(p-tolylsulfinylmethyl)piperidine 
• 292045-87-5 (4bR,9aS,10aS)-10a-Methyl-1,2,3,9,9a,10a-hexahydro-4bH-10-oxa-4a-aza-indeno[1,2-a]indene-4-thione 
• 263241-24-3 (SR)-2-(p-tolylsulfinylmethyl)-2,3,4,5-tetrahydropyridine N-oxide 
• 263241-23-2 2-((R)-Toluene-4-sulfinylmethyl)-piperidin-1-ol 
• 226545-90-0 (3R,8aS)-2,2,8a-Trimethyl-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-thione 

Relevant articles and documents

Four-Step Total Synthesis of (+)-Euphococcinine and (±)-Adaline

A four-step enantiospecific total synthesis of bicyclic homotropinone alkaloid euphococcinine and a racemic synthesis of adaline were reported. Key reactions in the synthesis are the diastereoselective addition of a Wittig phosphorene to the ketimines derived from Davis-Ellman sulfinamides, ring-closing metathesis, and intramolecular Michael reactions.

Asymmetrie synthesis of substituted homotropinones from W-Sulfinyl β-Amino ketone ketals. (-)-Euphococcinine and (-)-Adaline

Sulflnlmlne-derived N-sulflnyl βamlno ketone ketals on heating with NH4OAc:HOAc undergo a four-step intramolecular Mannich cyclization cascade reaction to give homotroplnones, such as (-)-euphococclnlne, in excellent yields as single isomers. 10.1021/ol902910w

An efficient, asymmetric synthesis of (+)-euphococcinine

The enantioselective synthesis of (+)-euphococcinine (1), a homotropane alkaloid, has been achieved in five steps from bicyclic lactam 5. (C) 2000 Elsevier Science Ltd.