Cas 459836-12-5,[(benzyl-methyl-amino)-(2,3-dimethoxy-quinoxalin-5-yl)-methyl]-phosphonic acid dimethyl ester

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Check Digit Verification of cas no

The CAS Registry Mumber 459836-12-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,9,8,3 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 459836-12:
(8*4)+(7*5)+(6*9)+(5*8)+(4*3)+(3*6)+(2*1)+(1*2)=195
195 % 10 = 5
So 459836-12-5 is a valid CAS Registry Number.

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459836-12-5Relevant academic research and scientific papers

5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition

Auberson, Yves P,Allgeier, Hans,Bischoff, Serge,Lingenhoehl, Kurt,Moretti, Robert,Schmutz, Markus

, p. 1099 - 1102 (2007/10/03)

NMDA antagonists derived from 5-phosphonomethyl-1,4-dihydroquinoxaline-2,3-dione (3a) are potent anticonvulsant agents, and display strong protective effects in the electroshock-induced convulsion assay in mice. Their preference for the human NMDAR 1A/2A over 1A/2B subunit composition was optimized, leading to (1RS,1′S)-PEAQX (9r), which shows a >100-fold selectivity.

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