460-75-3

Basic information

• Product Name: 2-(Trifluoromethyl)acetamide
• Synonyms: 2-(Trifluoromethyl)acetamide;3,3,3-Trifluoropropionamide;3,3,3-Trifluoropropanamide
• CAS NO: 460-75-3
• Molecular Formula: C₃H₄F₃NO
• Molecular Weight: 127.065
• Product Categories: Fluorine series
• Mol File: 460-75-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 109℃
• Boiling Point: 183℃
• Flash Point: 65℃
• Appearance: /
• Density: 1.334
• PKA: 14.91±0.40(Predicted)
• CAS DataBase Reference: 2-(Trifluoromethyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Trifluoromethyl)acetamide(460-75-3)
• EPA Substance Registry System: 2-(Trifluoromethyl)acetamide(460-75-3)

Safety Data

• Hazardous Substances Data: 460-75-3(Hazardous Substances Data)

Usage

General Description

2-(Trifluoromethyl)acetamide, also known as TFAA, is a chemical compound with the molecular formula C4H5F3NO. It is a colorless liquid with a pungent odor and is commonly used as a reagent in organic synthesis. TFAA is often used as a building block in the pharmaceutical and agrochemical industries, as well as in the production of fluorinated compounds. It is also employed as a solvent and intermediate in various chemical reactions. TFAA has a wide range of applications and is known for its high reactivity and stability, making it a valuable compound in the field of organic chemistry.

Upstream product

• 433-26-1 1,1,1-trifluoro-3-diazo-2-oxopropane 
• 41463-83-6 3,3,3-trifluoropropanoyl chloride 

Downstream Products

• 753-90-2 trifluoroethylamine 
• 432-74-6 2,3-dibromo-3,3-difluoro-propionic acid bromoamide 
• 460-39-9 3,3,3-trifluoropropylamine 

Relevant articles and documents

Method for producing 3, 3, 3 - [...] (by machine translation)

PROBLEM TO BE SOLVED: To provide a simple, efficient and inexpensive method capable of manufacturing a 3,3,3-trifluoro propionyl compound useful as a pharmaceutical and agricultural synthetic intermediate in an industrial scale.SOLUTION: There is provided a method of manufacturing a compound represented by the formula [1] by reacting a compound represented by the formula [2] with a polar compound after hydrolysis with using sulfuric acid. In the formula [1], X is Cl, OH, ORor NRR, Ris a Cto Calkyl group, a Cto Chalogenated alkyl group or phenyl group, Rand Rmay be same or different and are each independently a hydrogen, a Cto Calkyl group, a Cto Chalogenated alkyl group or phenyl group and each may together form a ring structure.

Halogenoalkylcarbamic acid ester pesticides

Halogenoalkylcarbamic acid esters of the formula STR1 in which R, R1 and R2 independently of one another represent methyl which is optionally substituted by halogen, at least one of the methyl groups R, R1 and R2 being substituted by at least one halogen atom, R3, R4 and R5 are identical or different and individually represent hydrogen or optionally substituted alkyl and n represents 0 or 1, synergize the action of known arthropodicides.