4600-82-2Relevant academic research and scientific papers
1,2-disubstituted 1,4-dihydro-4-oxoquinoline compounds
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, (2008/06/13)
The present invention relates to substituted 1,4-dihydro-4-oxoquinolines having antiviral activity. The substituents are present at positions 1, 2 and at least one of 5-8 positions of the quinoline ring.
A putatively unfeasible Heck reaction - From cyclopentenones to annulated ring systems
Dyker, Gerald,Markwitz, Hardy,Henkel, Gerald
, p. 2415 - 2423 (2007/10/03)
2-Iodocyclopentenones undergo a Heck reaction with allylic and homoallylic alcohols, in acceptable yields, to give dicarbonyl compounds useful for the construction of annulated cyclopentanones. In contrast, the corresponding iodo-substituted cyclohexenones, cycloheptenones and acyclic α,β-unsaturated ketones are far less or even unsuitable for Heck reactions of this type.
SCHWEFELVERBINDUNGEN DES ERDOELS XXII. ALKYL-10,11-DIHYDRODIINDENOTHIOPHENE
Boberg, Friedrich,Deters, Karin,Schulz, Juergen,Torges, Karl-Franz
, p. 69 - 80 (2007/10/03)
The one-pot syntheses of alkyl-10,11-dihydrodiindenothiophenes (3) by bromination and sulfurization of alkylindan-1-ones without substituents at C-2 (1) has been studied with 14 1 with C1-C4-rests at the benzene and or the cyclopentane ring. 9 dialkyl-3 and 3 tetraalkyl-3 are prepared in yields of 7-66percent; an octamethyl-3 is detected by tlc and ms. 2 dialkyl-3 are prepared too by an independent syntheses from dimethyl 2,5-bis(methylphenyl)thiophene-3,4-dicarboxylates (13).The mechanism of the one-pot syntheses, which gives diindeno-1,4-dithiines too,is discussed.The oxidation of 4 3 has been studied.Key words: Alkylindan-1-ones, alkyl-10,11-dihydrodiindenothiophenes, alkyldiindeno-1,4-dithiines, one-pot syntheses of anellated thiophenes, oxidation of anellated thiophenes.
