64740-36-9

Usage

Uses

Used in Pharmaceutical Industry:
3-(4-Ethylphenyl)propionic acid is used as an analgesic for the relief of mild to moderate pain, such as headaches, muscle aches, and menstrual cramps. It is valued for its ability to provide quick and effective pain relief without the need for a prescription.
Used in Antipyretic Applications:
In the healthcare sector, 3-(4-Ethylphenyl)propionic acid serves as an antipyretic to reduce fever by lowering the body's temperature set point, thus helping to alleviate the discomfort associated with feverish conditions.
Used in Anti-inflammatory Applications:
3-(4-Ethylphenyl)propionic acid is utilized as an anti-inflammatory agent to decrease inflammation in various conditions such as arthritis, where it can help to reduce swelling and improve joint mobility.
Used in Over-the-Counter Medications:
3-(4-Ethylphenyl)propionic acid is a key component in a variety of over-the-counter medications, making it accessible to consumers for self-treatment of common ailments without the need for a healthcare provider's intervention.

InChI:InChI=1/C11H14O2/c1-2-9-3-5-10(6-4-9)7-8-11(12)13/h3-6H,2,7-8H2,1H3,(H,12,13)

Upstream product

• 100-41-4 ethylbenzene 
• 124-40-3 dimethyl amine 
• 104175-15-7 3-(4-ethylphenyl)propanal 
• 124-38-9 carbon dioxide 
• 64740-42-7 1-Ethyl-4-(2-phenylsulfanyl-ethyl)-benzene 
• 27465-51-6 1-(4-ethylphenyl)-1-propanone 
• 63134-93-0 tetraethyl <1,4-phenylenebis(methylene)>bismalonate 
• 351015-27-5 4-ethylbenzylmalonic acid 
• 4748-78-1 4-ethylbenzylaldehyde 
• 198341-20-7 ethyl 3‐(4‐ethylphenyl)acrylate 
• 120680-98-0 4-ethylcinnamic acid 
• 3454-07-7 1-ethenyl-4-ethyl-benzene 
• 1467-05-6 4-ethylbenzylchloride 
• 37765-74-5 diethyl 4-ethylbenzylmalonate 

Downstream Products

• 351014-45-4 vinyl 3-(4-ethylphenyl)propanoate 
• 1227418-21-4 C₁₇H₂₀O₅ 
• 52689-24-4 5-Ethylindan 
• 180274-13-9 3-(4-ethylphenyl)propan-1-ol 
• 1027964-15-3 2-Benzylamino-7-ethyl-1,2,3,4-tetrahydro-naphthalene-2-carbonitrile 
• 1026579-27-0 (2-Aminomethyl-7-ethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-benzyl-amine 
• 1026740-44-2 Benzyl-(7-ethyl-3,4-dihydro-naphthalen-2-yl)-amine 
• 4600-82-2 5-ethylindan-1-one 
• 859967-01-4 3-(4-ethyl-phenyl)-propionic acid pentyl ester 
• 42348-88-9 6-ethyl-1-indanone 
• 1412452-68-6 C₂₁H₂₇N₅O₂ 

Relevant academic research and scientific papers

Improved synthesis of natural ester sintenin and its analogues via Wittig reaction

The synthesis of a cytotoxic natural ester sintenin (7a) and twenty eight of its analogues including nitrogen-containing heterocyclic indole moiety (7b-7t), saturated (10a-10d) and unsaturated (10e-10h) amides were carried out by convenient route via one-pot Wittig reaction in aqueous medium with improved yield. A systematic structure activity relationship of sintenin ester was designed by chemically modified derivatives in order to get better cytotoxicity.

The effect of vinyl esters on the enantioselectivity of the lipase-catalysed transesterification of alcohols

The enantioselectivity of the lipase from Pseudomonas cepacia (PCL) in the transesterification of 2-phenyl-1-propanol 1 was studied using a series of vinyl 3-arylpropanoates as acyl donors. The most enantioselective transesterification reaction of the alcohol was attained by using vinyl 3-(p-iodophenyl)- or 3-(p-trifluoromethylphenyl)propanoates, with enantiomer ratios, E, of 116 and 138, respectively. Vinyl 3-phenylpropanoate was also effective for the resolution of 1 mediated by lipases from P. fluorescens and porcine pancreas and for the PCL-catalysed transesterification of several 2-phenyl-1-alkanols. The enantiomeric resolution of 1 was practically carried out by the first enantioselective transesterification using PCL and vinyl 3-(p-iodophenyl)propanoate to afford (R)-1 and then the enantioselective hydrolysis of the resultant ester to afford (S)-1.