4600-95-7Relevant articles and documents
Organocatalytic enantioselective oxidative C-H alkenylation and arylation of N-Carbamoyl tetrahydropyridines and tetrahydro-β-carbolines
Liu, Xigong,Meng, Zhilin,Li, Chengkun,Lou, Hongxiang,Liu, Lei
, p. 6012 - 6015 (2015/05/13)
The first organocatalytic enantioselective C-H alkenylation and arylation reactions of N-carbamoyl tetrahydropyridines and tetrahydro-β-carbolines (THCs) are described. The metal-free processes represent an efficient and straightforward approach to a variety of structurally and electronically diverse α-substituted tetrahydropyridines and THCs in good yields with excellent regio- and enantioselectivities. Preliminary control experiments provide important insights into the reaction mechanism.
Studies on Psychotropic Agents. VI. Synthesis of 1'-Methylspiro-3-one and Related Compounds
Nagai, Yasutaka,Hino, Katsuhiko,Uno, Hitoshi,Minami, Shinsaku
, p. 1387 - 1393 (2007/10/02)
The title compounds (19) were synthesized by rearrangement of the 1-ethoxycarbonyl-4-aryl-3,4-epoxypiperidines (7) to give the 3-aryl-3-formylpyrrolidine derivatives (12) for pharmacological testing.Compound (19b) exhibited moderate central nervous system