460050-73-1Relevant articles and documents
Design and Applications of N-tert-Butyl Sulfinyl Squaramide Catalysts
Li, Yao,He, Cyndi Qixin,Gao, Fei-Xiang,Li, Zhen,Xue, Xiao-Song,Li, Xin,Houk,Cheng, Jin-Pei
supporting information, p. 1926 - 1929 (2017/04/13)
A new chiral HBD system, N-tert-butyl sulfinyl squaramide, was designed and synthesized. The core N-tert-butyl sulfinyl squaramide with an 1-aminoindan-2-ol skeleton was found to be an efficient catalyst in the enantioselective Friedel-Crafts alkylation of indoles and acyl phosphonates.
Catalytic enantioselective Friedel-Crafts alkylation of indoles with β,γ-unsaturated α-keto phosphonates in the presence of Chiral palladium complexes
Kang, Young Ku,Suh, Ki Hyung,Kim, Dae Young
experimental part, p. 1125 - 1128 (2011/06/21)
The catalytic enantioselective Friedel-Crafts alkylation reaction promoted by chiral palladium complexes is described. The treatment of indoles with β,γ-unsaturated α-keto phosphonates under the mild reaction conditions afforded the corresponding Friedel-Crafts alkylation adducts with excellent enantioselectivities (up to 99% ee). Georg Thieme Verlag Stuttgart - New York.
Asymmetric conjugate addition of silyl enol ethers catalyzed by tethered bis(8-quinolinolato) aluminum complexes
Takenaka, Norito,Abell, Joshua P.,Yamamoto, Hisashi
, p. 742 - 743 (2007/10/03)
New chiral tethered bis(8-quinolinolato) (TBOx) aluminum(III) complexes effectively catalyze the highly enantioselective Mukaiyama-Michael reaction of silyl enol ethers, including tetrasubstituted enolates that give rise to enantioenriched α-carbonyl all-
Enantioselective friedel-crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes
Evans, David A.,Fandrick, Keith R.,Song, Hyun-Ji,Scheidt, Karl A.,Xu, Risheng
, p. 10029 - 10041 (2008/03/12)
The enantioselective Friedel-Crafts addition of a variety of indoles catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes (Sc(III)-pybox) was accomplished utilizing a series of β-substituted α,β-unsaturated phosphonates and α,β-unsaturate
Enantioselective indole Friedel-Crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes
Evans, David A.,Scheidt, Karl A.,Fandrick, Keith R.,Lam, Hon Wai,Wu, Jimmy
, p. 10780 - 10781 (2007/10/03)
A highly enantioselective Friedel-Crafts alkylation of electron-rich aromatic nucleophiles catalyzed by scandium(III) triflate-pyridyl(bis)oxazoline complexes has been accomplished. The reaction involves α,β-unsaturated acyl phosphonates as electrophiles and primarily substituted indoles as nucleophiles. The reactive acyl phosphonate product is converted to the corresponding ester or amide in good overall yield by adding an alcohol or amine directly to the reaction mixture. Copyright
