46035-60-3 Usage
Synonyms
1-methyl-1H-benzimidazole-7-diamine
Molecular Weight
147.18 g/mol
Structure
A benzimidazole derivative with two amine groups (-NH2) at positions 2 and 5, and a methyl group (-CH3) at position 1.
Class
Organic compound, specifically an aniline and substituted aniline.
Physical State
Likely a solid at room temperature, based on its molecular weight and structure.
Industrial Applications
a. Building block in the synthesis of pharmaceuticals and agrochemicals.
b. Intermediate in the manufacture of dyes, pigments, and other specialty chemicals.
Medicinal Chemistry
Potential applications in the development of new drugs targeting various diseases.
Hazardous Properties
Information on hazardous properties is not provided in the material, but it is important to consider potential hazards when handling chemicals, such as toxicity, flammability, or reactivity.
Storage and Handling
Appropriate storage and handling conditions are not provided in the material, but it is crucial to follow safety guidelines and regulations when storing and handling chemicals, such as using appropriate containment and protective equipment.
Check Digit Verification of cas no
The CAS Registry Mumber 46035-60-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,6,0,3 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 46035-60:
(7*4)+(6*6)+(5*0)+(4*3)+(3*5)+(2*6)+(1*0)=103
103 % 10 = 3
So 46035-60-3 is a valid CAS Registry Number.
46035-60-3Relevant academic research and scientific papers
2-amino-X-nitrobenzimidazoles as precursors of food-borne carcinogens: A new approach to IQ synthesis
Bella, Maros,Milata, Viktor,Larina, Lyudmila I.
experimental part, p. 293 - 296 (2012/06/04)
Cyclization of (non)-methylated nitro-o-phenylenediamines with cyanogen bromide provided nitro-substituted 2-aminobenzimidazoles in good up to excellent yields. Catalytic hydrogenation of 2-amino-1-methyl-5-nitrobenzimidazole yielded 2,5-diamino-1-methylbenzimidazole, which on treatment with 1,1,3,3-tetramethoxypropane in methanol and subsequently after removal of methanol in polyphosphoric acid afforded food-borne carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in 20% yield. Copyright
DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS
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Page/Page column 109; 106-107; 60, (2010/02/07)
Benzimidazole derivatives of formula (I) , which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such benzimidazole derivatives as well as methods of using the same in the treatme
