460743-50-4Relevant academic research and scientific papers
Chiral bicyclic guanidines: A concise and efficient aziridine-based synthesis
Ye, Weiping,Leow, Dasheng,Goh, Serena Li Min,Tan, Chin-Tong,Chian, Chee-Hoe,Tan, Choon-Hong
, p. 1007 - 1010 (2007/10/03)
A series of chiral bicyclic guanidines, either symmetrical or non-symmetrical, was synthesized using a concise and efficient aziridine-based synthetic methodology. Starting from commercial amino alcohols, five synthetic steps were performed, with only thr
Bifurcated, modular syntheses of chiral annulet triazacyclononanes.
Argouarch, Gilles,Stones, Graham,Gibson, Colin L,Kennedy, Alan R,Sherrington, David C
, p. 4408 - 4417 (2007/10/03)
Three chiral 2,6-disubstituted tri-N-methyl azamacrocycles have been prepared by modular methods. These macrocycles were accessed from three chiral 1,4,7-triazaheptanes intermediates that were prepared by two independent routes. The first of these routes
Solvent-mediated selective single and double ring-opening of N-tosyl-activated aziridines using benzylamine
Scheuermann,Ilyashenko, Gennadiy,Griffiths,Watkinson, Michael
, p. 269 - 272 (2007/10/03)
An efficient methodology has been developed for the synthesis of a series of new diamine 2 and triamine ligands 3 for application in asymmetric catalysis via selective single or double ring-opening of tosylaziridines 1, which are derived from chiral pool
The synthesis of chiral annulet 1,4,7-triazacyclononanes
Argouarch, Gilles,Gibson, Colin L,Stones, Graham,Sherrington, David C
, p. 3795 - 3798 (2007/10/03)
Novel and flexible routes for the synthesis of chiral ring annulet 2,6-disubstituted 1,4,7-trimethyl-1,4,7-triazamacrocycles are described. Efficient macrocyclisations were realised provided that chiral analogues of N,N-bis-[2-(toluene-sulfonylamino)ethyl]-toluene-4-sulfonamide were used as the nucleophilic components. Complexes prepared, in situ, from these 2,6-disubstituted 1,4,7-trimethyl-1,4,7-triazamacrocycles and manganese(II) catalysed the asymmetric epoxidation of styrene with hydrogen peroxide.
Sulfonamide ligands from chiral aziridines - Application to the titanium-mediated addition of diethylzinc to benzaldehyde
Lake, Fredrik,Moberg, Christina
, p. 3179 - 3188 (2007/10/03)
A modular approach was developed for the preparation of chiral, enantiopure sulfonamide ligands with C1, C2, and C3 symmetry by ring opening of chiral N-sulfonylaziridines with ammonia, primary amines, and diamines. The new ligands were assessed in the titanium-mediated addition of diethylzinc to benzaldehyde, giving the product with selectivities up to 76% ee. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.
