460745-04-4

Basic information

• Product Name: (2RS,4S)-4-[(3'S,4'R)-4'-(tert-butyldimethylsiloxy)-3'-hydroxy-1'-hexadecynyl]-2-phenyl-1,3-dioxolane
• Synonyms: (2RS,4S)-4-[(3'S,4'R)-4'-(tert-butyldimethylsiloxy)-3'-hydroxy-1'-hexadecynyl]-2-phenyl-1,3-dioxolane
• CAS NO: 460745-04-4
• Molecular Weight: 516.837
• Mol File: 460745-04-4.mol

Chemical Properties

• CAS DataBase Reference: (2RS,4S)-4-[(3'S,4'R)-4'-(tert-butyldimethylsiloxy)-3'-hydroxy-1'-hexadecynyl]-2-phenyl-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: (2RS,4S)-4-[(3'S,4'R)-4'-(tert-butyldimethylsiloxy)-3'-hydroxy-1'-hexadecynyl]-2-phenyl-1,3-dioxolane(460745-04-4)
• EPA Substance Registry System: (2RS,4S)-4-[(3'S,4'R)-4'-(tert-butyldimethylsiloxy)-3'-hydroxy-1'-hexadecynyl]-2-phenyl-1,3-dioxolane(460745-04-4)

Safety Data

• Hazardous Substances Data: 460745-04-4(Hazardous Substances Data)

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 131905-86-7 (S)-but-3-yne-1,2-diol 
• 114379-26-9 (R)-2-hydroxytetradecanal tert-butyldimethylsilyl ether 

Downstream Products

• 636596-82-2 (4S)-4-[(3'S,4'R)-4'-(tert-butyldimethylsilyloxy)-3'-hydroxyoctadecanyl]-2-phenyl-1,3-dioxolane 
• 636596-83-3 (4S)-4-[(3'S,4'R)-4'-(tert-butyldimethylsilyloxy)-3'-(p-toluenesulfonyloxy)octadecanyl]-2-phenyl-1,3-dioxolane 
• 636596-81-1 (2S,5S,6R)-6-(tert-butyldimethylsilyloxy)-2,5-dihydroxyoctadecanyl 2',4',6'-triisopropylbenzenesulfonate 

Relevant articles and documents

Highly stereoselective and stereodivergent synthesis of four types of THF cores in acetogenins using a C4-chiral building block

(Formula Presented) Four stereoisomers of the THF cores, synthetic intermediates of acetogenins, have been synthesized with high diastereoselectivity by asymmetric alkynylation and subsequent stereodivergent THF ring formation. The asymmetric alkynylation