460986-39-4Relevant academic research and scientific papers
Design, synthesis, and herbicidal activity of novel substituted 3-(pyridin-2-yl)benzenesulfonamide derivatives
Xie, Yong,Chi, Hui-Wei,Guan, Ai-Ying,Liu, Chang-Ling,Ma, Hong-Juan,Cui, Dong-Liang
, p. 12491 - 12496 (2015/04/21)
A series of novel substituted 3-(pyridin-2-yl)benzenesulfonamide derivatives were designed and synthesized using 2-phenylpridines as the lead compound by intermediate derivatization methods in an attempt to obtain novel compound candidates for weed contro
Synthesis and herbicidal activity of phenylpyridines - A new lead
Schaefer, Peter,Hamprecht, Gerhard,Puhl, Michael,Westphalen, Karl-Otto,Zagar, Cyrill
, p. 715 - 719 (2007/10/03)
Novel phenylpyridines were synthesized based on molecular modeling oriented design by super-position of herbicidal phenyl-uracils, -indazoles, and diphenylethers. Their preparation follows Suzuki-type coupling conditions of reactive 2-chloro-pyridines with appropriate 2,5-substituted 4-chloro-phenyl boronic acids. Depending on the nature of substituents in the pyridine, and in particular the phenyl group, a large number of derivatives are readily accessible. Besides open-chain phenylpyridines also anellated compounds, such as pyridine-substituted 2H-1,4-benzothiazin-3(4H)-one or 3,4-dihydro-1H- quinolin-2-one, were prepared. Phenylpyridines act by inhibition of protoporphyrinogen-IX-oxidase. Their synthesis will be described in conjunction with structure-activity relationships. Phenylpyridines are highly active against many important broadleaf and grass weed species under pre- and - in particular - post-emergent conditions.
