461383-58-4

Upstream product

• 461383-57-3 methyl 4-azido-4-phenylbutanoate 
• 2046-17-5 methyl 3-(benzyl)propanoate 
• 19078-76-3 methyl 4-bromo-4-phenylbutanoate 
• 1008-76-0 4,5-dihydro-5-phenyl-2(3H)-furanone 
• 1821-12-1 4-Phenylbutyric acid 

Downstream Products

• 461383-59-5 4-azido-4-phenylbutanoyl chloride 
• 461383-66-4 S-(2-iodophenethyl) 4-azido-4-phenylbutanethioate 
• 22050-10-8 (+/-)-5-phenyl-2-pyrrolidinone 

Relevant academic research and scientific papers

Iron-catalyzed ring-opening azidation and allylation of O-heterocycles

We have established the first catalytic C-C and C-N bond formation reactions of O-heterocycles (e.g., tetrahydrofuran, phthalane, and lactone derivatives) using iron trichloride as a catalyst in the presence of TMSN 3 or allylsilanes accompanie

Intramolecular Cyclization of Acyl Radicals onto the Azido Group: A New Radical Approach to Cyclized Lactams

(Equation Presented) Reagents: i, Bu3SnH/AlBN; ii, (TMS)3SiH/AlBN. Aryl- and alkyl-derived azidoacyl radicals, generated from thiolesters by intramolecular homolytic substitution at the sulfur, can undergo five- and six-membered cyclization onto the azido moiety to give cyclized lactams.