461389-77-5

Upstream product

• 110-89-4 piperidine 
• 612-15-7 o-methoxystyrene 
• 28033-63-8 2-(2-methoxyphenyl)acetyl chloride 
• 349134-81-2 2-(2-methoxyphenyl)-1-(piperidin-1-yl)ethan-1-one 

Downstream Products

• 461389-80-0 1-[2-(2-hydroxyphenyl)ethyl]piperidine 

Relevant academic research and scientific papers

A potassium magnesiate complex: Synthesis, structure and catalytic intermolecular hydroamination of styrenes

A new heterobimetallic potassium magnesiate complex KMg[N(SiMe3)2]2Bn (Bn = PhCH2-) was synthesized by simply mixing magnesium amide and potassium benzyl in toluene. The TMEDA-ligated potassium magnesiate comple

Synthesis and cholinesterase activity of phenylcarbamates related to Rivastigmine, a therapeutic agent for Alzheimer's disease

In order to develop new cholinesterase agents effective against Alzheimer's disease (AD) we synthesized some phenylcarbamates structurally related to Rivastigmine and evaluated their in vitro and in vivo biological activity. Among the compounds which displayed the most significant in vitro activity, 1-[1-(3-dimethylcarbamoyloxyphenyl)ethyl]piperidine (31b), in addition to a simple and cheaper synthesis, showed lower toxicity and very similar therapeutic index in comparison with Rivastigmine.