462-73-7

Usage

Uses

Used in Chemical Research:
1-Chloro-4-fluorobutane is used as a reagent in chemical research for its unique properties and reactivity, facilitating the synthesis of various organic compounds.
Used in Pharmaceutical Production:
1-Chloro-4-fluorobutane is used as an intermediate in the production of pharmaceuticals, contributing to the development of new drugs and medicines.
Used in the Synthesis of Organic Compounds:
Due to its chemical reactivity, 1-Chloro-4-fluorobutane is used as a building block in the synthesis of a wide range of organic compounds, including specialty chemicals and materials.
Safety and Storage:
1-Chloro-4-fluorobutane should be stored in a cool, dry, and well-ventilated place, away from heat sources and open flames to prevent potential hazards. It is essential to handle this chemical substance under controlled conditions and with appropriate personal protective equipment to ensure safety.

InChI:InChI=1/C4H8ClF/c5-3-1-2-4-6/h1-4H2

Upstream product

• 26910-61-2 4-chlorobutyl methanesulfonate 
• 110-56-5 1,4-dichlorobutane 
• 13617-19-1 1-chloro-4-trimethylsilanyloxy-butane 
• 6940-78-9 4-chlorobutyl bromide 
• 2366-52-1 1-fluorobutane 
• 928-51-8 4-Chloro-1-butanol 
• 107-21-1 ethylene glycol 

Downstream Products

• 353-13-9 5-fluoro-valeronitrile 
• 372-91-8 1-fluoro-4-iodobutane 
• 373-16-0 6-fluorohex-1-yne 
• 1019209-49-4 1-[3-(4-fluorobutylamino)-phenyl]-ethanone 

Relevant academic research and scientific papers

REACTIONS OF HALOGEN FLUORIDES. XI. MECHANISM OF REACTIONS OF ALKYL HALIDES WITH BROMINE TRIFLUORIDE

The effects of the substituted halogen, the neighboring groups, and the polarity of the medium on the nature of the fluorination products were studied for the reactions of δ-substituted halogenobutanes and 1,2,3-trihalogenobutanes with bromine tetrachloride.A mechanism involving formation of linear halogenonium ions at the rate-determining stage is proposed.

FLUORINATION OF HALOGENO ALCOHOLS WITH 1,1,2,3,3,3-HEXAFLUOROPROPYL DIETHYLAMINE

Fluorination of halogeno alcohols with 1,1,2,3,3,3-hexafluoropropyl diethylamine (PPDA) was investigated. 2-Bromo-1-fluorobutane was obtained from the reaction of PPDA and 2-bromo-1-butanol (yield 50percent).Similar results were obtained from other alipha

Free Radical Substitution. Part 37. The Effect of Solvent on the Atomic Chlorination of 1-Substituted Butanes and Related Compounds

Experimental results reported in this paper show that the relative selectivity of atomic chlorination of 1-substituted butanes and related compounds is greatly influenced by the phase and by solvents.Solvents can be divided into three classes: (a) inert, (b) solvents which decrease the selectivity, and (c) solvents which increase the selectivity.The second group solvate the transition state and the third group solvate the chlorine atoms.